Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies

A.J. Van De Loo; K. Knipping; M. Mackus; A.D. Kraneveld; J. Garssen; A. Scholey; G. Bruce; J.C. Verster

doi:10.1111/acer.13833

Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies

A.J. Van De Loo, K. Knipping, M. Mackus, A.D. Kraneveld, J. Garssen, A. Scholey, G. Bruce, J.C. Verster

Research output: Contribution to conference › Poster › Academic

Abstract

Background: Previous research has reported changes in blood cytokine concentrations both after consumption of alcohol, and during the alcohol hangover phase. The aimof the current two studies was to further elucidate how alcohol and alcohol hangover influences salivary cytokine concentration in healthy participants. Methods: In study 1 (N = 15) participants consumed alcohol on the test day and placebo on the control day. Saliva was collected every hour for 8 h. In study 2 (N = 35), saliva was collected the morning following an evening of alcohol consumption (mean of 8.48 +/-1.39 h after stopping with drinking) and on an alcohol-free control day. In both studies cytokine concentrations that could be reliably assessed (IL-1b, IL-8, TNF-a in both studies, and IL-6, IL-10 in study 2 only) were compared between both test days. Results: Directly after consuming alcohol (study 1) significant increases in pro-inflammatory cytokines (IL-1b, Il-8) were found on multiple timepoints (p

Original language	English
DOIs	https://doi.org/10.1111/acer.13833
Publication status	Published - 1 Aug 2018
Event	19th Worldwide congress of International society for biomedical research on alcoholism: ISBRA2018 - Kyoto, Japan Duration: 9 Sept 2018 → 13 Sept 2018

Conference

Conference	19th Worldwide congress of International society for biomedical research on alcoholism
Abbreviated title	ISBRA2018
Country/Territory	Japan
City	Kyoto
Period	9/09/18 → 13/09/18

Keywords

alcohol
endogenous compound
interleukin 10
interleukin 1beta
interleukin 6
interleukin 8
placebo
tumor necrosis factor
adult
alcohol consumption
clinical article
conference abstract
controlled study
cytokine response
drinking
female
hangover
human
human tissue
immune system
male
preliminary data
saliva

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10.1111/acer.13833

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Van De Loo, A. J., Knipping, K., Mackus, M., Kraneveld, A. D., Garssen, J., Scholey, A., Bruce, G., & Verster, J. C. (2018). Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies. Poster session presented at 19th Worldwide congress of International society for biomedical research on alcoholism, Kyoto, Japan. https://doi.org/10.1111/acer.13833

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title = "Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies",

abstract = "Background: Previous research has reported changes in blood cytokine concentrations both after consumption of alcohol, and during the alcohol hangover phase. The aimof the current two studies was to further elucidate how alcohol and alcohol hangover influences salivary cytokine concentration in healthy participants. Methods: In study 1 (N = 15) participants consumed alcohol on the test day and placebo on the control day. Saliva was collected every hour for 8 h. In study 2 (N = 35), saliva was collected the morning following an evening of alcohol consumption (mean of 8.48 +/-1.39 h after stopping with drinking) and on an alcohol-free control day. In both studies cytokine concentrations that could be reliably assessed (IL-1b, IL-8, TNF-a in both studies, and IL-6, IL-10 in study 2 only) were compared between both test days. Results: Directly after consuming alcohol (study 1) significant increases in pro-inflammatory cytokines (IL-1b, Il-8) were found on multiple timepoints (p",

keywords = "alcohol, endogenous compound, interleukin 10, interleukin 1beta, interleukin 6, interleukin 8, placebo, tumor necrosis factor, adult, alcohol consumption, clinical article, conference abstract, controlled study, cytokine response, drinking, female, hangover, human, human tissue, immune system, male, preliminary data, saliva",

author = "{Van De Loo}, A.J. and K. Knipping and M. Mackus and A.D. Kraneveld and J. Garssen and A. Scholey and G. Bruce and J.C. Verster",

year = "2018",

month = aug,

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doi = "10.1111/acer.13833",

language = "English",

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Van De Loo, AJ, Knipping, K, Mackus, M, Kraneveld, AD , Garssen, J, Scholey, A, Bruce, G & Verster, JC 2018, 'Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies', 19th Worldwide congress of International society for biomedical research on alcoholism, Kyoto, Japan, 9/09/18 - 13/09/18. https://doi.org/10.1111/acer.13833

Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies. / Van De Loo, A.J.; Knipping, K.; Mackus, M. et al.
2018. Poster session presented at 19th Worldwide congress of International society for biomedical research on alcoholism, Kyoto, Japan.

Research output: Contribution to conference › Poster › Academic

TY - CONF

T1 - Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies

AU - Van De Loo, A.J.

AU - Knipping, K.

AU - Mackus, M.

AU - Kraneveld, A.D.

AU - Garssen, J.

AU - Scholey, A.

AU - Bruce, G.

AU - Verster, J.C.

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Background: Previous research has reported changes in blood cytokine concentrations both after consumption of alcohol, and during the alcohol hangover phase. The aimof the current two studies was to further elucidate how alcohol and alcohol hangover influences salivary cytokine concentration in healthy participants. Methods: In study 1 (N = 15) participants consumed alcohol on the test day and placebo on the control day. Saliva was collected every hour for 8 h. In study 2 (N = 35), saliva was collected the morning following an evening of alcohol consumption (mean of 8.48 +/-1.39 h after stopping with drinking) and on an alcohol-free control day. In both studies cytokine concentrations that could be reliably assessed (IL-1b, IL-8, TNF-a in both studies, and IL-6, IL-10 in study 2 only) were compared between both test days. Results: Directly after consuming alcohol (study 1) significant increases in pro-inflammatory cytokines (IL-1b, Il-8) were found on multiple timepoints (p

AB - Background: Previous research has reported changes in blood cytokine concentrations both after consumption of alcohol, and during the alcohol hangover phase. The aimof the current two studies was to further elucidate how alcohol and alcohol hangover influences salivary cytokine concentration in healthy participants. Methods: In study 1 (N = 15) participants consumed alcohol on the test day and placebo on the control day. Saliva was collected every hour for 8 h. In study 2 (N = 35), saliva was collected the morning following an evening of alcohol consumption (mean of 8.48 +/-1.39 h after stopping with drinking) and on an alcohol-free control day. In both studies cytokine concentrations that could be reliably assessed (IL-1b, IL-8, TNF-a in both studies, and IL-6, IL-10 in study 2 only) were compared between both test days. Results: Directly after consuming alcohol (study 1) significant increases in pro-inflammatory cytokines (IL-1b, Il-8) were found on multiple timepoints (p

KW - alcohol

KW - endogenous compound

KW - interleukin 10

KW - interleukin 1beta

KW - interleukin 6

KW - interleukin 8

KW - placebo

KW - tumor necrosis factor

KW - adult

KW - alcohol consumption

KW - clinical article

KW - conference abstract

KW - controlled study

KW - cytokine response

KW - drinking

KW - female

KW - hangover

KW - human

KW - human tissue

KW - immune system

KW - male

KW - preliminary data

KW - saliva

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DO - 10.1111/acer.13833

M3 - Poster

T2 - 19th Worldwide congress of International society for biomedical research on alcoholism

Y2 - 9 September 2018 through 13 September 2018

ER -

Van De Loo AJ, Knipping K, Mackus M, Kraneveld AD , Garssen J, Scholey A et al.. Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies. 2018. Poster session presented at 19th Worldwide congress of International society for biomedical research on alcoholism, Kyoto, Japan. doi: 10.1111/acer.13833

Differential effects on acute salivary cytokine response following alcohol consumption and alcohol hangover: Preliminary results from two independent studies

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