Developments in coupled solid-phase extraction-capillary electrophoresis 2011-2013

Rawi Ramautar; Govert W Somsen; Gerhardus J de Jong

doi:10.1002/elps.201300335

Developments in coupled solid-phase extraction-capillary electrophoresis 2011-2013

Rawi Ramautar, Govert W Somsen, Gerhardus J de Jong

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

This article presents an overview of the design and application of coupled SPE-CE systems that have been reported in the literature between January 2011 and June 2013. The present paper is an update of three previous review papers covering the years 2000-2011 (Electrophoresis 2008, 29, 108-128; Electrophoresis 2010, 31, 44-54; Electrophoresis 2012, 33, 243-250). The use of in-line and on-line SPE-CE approaches is described in this review. Emerging technological developments, such as the use of in-line frit-free SPE and chip-based SPE for extraction of sample components prior to CE analysis, are outlined. Selected examples illustrate the applicability of SPE-CE in biomedical, pharmaceutical, and environmental analysis. A complete overview of recent SPE-CE studies is given in table format, providing information on sample type, SPE sorbent, coupling mode, detection mode, and LOD. Finally, some general conclusions and future perspectives are provided.

Original language	English
Pages (from-to)	128-37
Number of pages	10
Journal	Electrophoresis
Volume	35
Issue number	1
DOIs	https://doi.org/10.1002/elps.201300335
Publication status	Published - Jan 2014

Bibliographical note

Keywords

DNA
Electrophoresis, Capillary
Limit of Detection
Peptides
Solid Phase Extraction

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Ramautar_et_al-2014-ELECTROPHORESIS
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Cite this

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title = "Developments in coupled solid-phase extraction-capillary electrophoresis 2011-2013",

abstract = "This article presents an overview of the design and application of coupled SPE-CE systems that have been reported in the literature between January 2011 and June 2013. The present paper is an update of three previous review papers covering the years 2000-2011 (Electrophoresis 2008, 29, 108-128; Electrophoresis 2010, 31, 44-54; Electrophoresis 2012, 33, 243-250). The use of in-line and on-line SPE-CE approaches is described in this review. Emerging technological developments, such as the use of in-line frit-free SPE and chip-based SPE for extraction of sample components prior to CE analysis, are outlined. Selected examples illustrate the applicability of SPE-CE in biomedical, pharmaceutical, and environmental analysis. A complete overview of recent SPE-CE studies is given in table format, providing information on sample type, SPE sorbent, coupling mode, detection mode, and LOD. Finally, some general conclusions and future perspectives are provided.",

keywords = "DNA, Electrophoresis, Capillary, Limit of Detection, Peptides, Solid Phase Extraction",

author = "Rawi Ramautar and Somsen, {Govert W} and {de Jong}, {Gerhardus J}",

note = "{\textcopyright} 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",

year = "2014",

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AB - This article presents an overview of the design and application of coupled SPE-CE systems that have been reported in the literature between January 2011 and June 2013. The present paper is an update of three previous review papers covering the years 2000-2011 (Electrophoresis 2008, 29, 108-128; Electrophoresis 2010, 31, 44-54; Electrophoresis 2012, 33, 243-250). The use of in-line and on-line SPE-CE approaches is described in this review. Emerging technological developments, such as the use of in-line frit-free SPE and chip-based SPE for extraction of sample components prior to CE analysis, are outlined. Selected examples illustrate the applicability of SPE-CE in biomedical, pharmaceutical, and environmental analysis. A complete overview of recent SPE-CE studies is given in table format, providing information on sample type, SPE sorbent, coupling mode, detection mode, and LOD. Finally, some general conclusions and future perspectives are provided.

KW - DNA

KW - Electrophoresis, Capillary

KW - Limit of Detection

KW - Peptides

KW - Solid Phase Extraction

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Developments in coupled solid-phase extraction-capillary electrophoresis 2011-2013

Abstract

Bibliographical note

Keywords

Access to Document

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