Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.

S.F. Teunissen; ML Vlaming; H. Rosing; J.H.M. Schellens; A.H. Schinkel; J.H. Beijnen

Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.

S.F. Teunissen, ML Vlaming, H. Rosing, J.H.M. Schellens, A.H. Schinkel, J.H. Beijnen

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Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	2362-2353
Journal	Journal of chromatography. B
Volume	878
Issue number	25
Publication status	Published - 2010

Cite this

Teunissen, S. F., Vlaming, ML., Rosing, H., Schellens, J. H. M., Schinkel, A. H., & Beijnen, J. H. (2010). Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice. Journal of chromatography. B, 878(25), 2362-2353.

Teunissen, S.F. ; Vlaming, ML ; Rosing, H. et al. / Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice. In: Journal of chromatography. B. 2010 ; Vol. 878, No. 25. pp. 2362-2353.

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title = "Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.",

author = "S.F. Teunissen and ML Vlaming and H. Rosing and J.H.M. Schellens and A.H. Schinkel and J.H. Beijnen",

year = "2010",

language = "English",

volume = "878",

pages = "2362--2353",

journal = "Journal of chromatography. B",

issn = "1873-376X",

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number = "25",

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Teunissen, SF, Vlaming, ML, Rosing, H, Schellens, JHM, Schinkel, AH & Beijnen, JH 2010, 'Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.', Journal of chromatography. B, vol. 878, no. 25, pp. 2362-2353.

Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice. / Teunissen, S.F.; Vlaming, ML; Rosing, H. et al.
In: Journal of chromatography. B, Vol. 878, No. 25, 2010, p. 2362-2353.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.

AU - Teunissen, S.F.

AU - Vlaming, ML

AU - Rosing, H.

AU - Schellens, J.H.M.

AU - Schinkel, A.H.

AU - Beijnen, J.H.

PY - 2010

Y1 - 2010

M3 - Article

SN - 1873-376X

VL - 878

SP - 2362

EP - 2353

JO - Journal of chromatography. B

JF - Journal of chromatography. B

IS - 25

ER -

Teunissen SF, Vlaming ML, Rosing H, Schellens JHM, Schinkel AH, Beijnen JH. Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice. Journal of chromatography. B. 2010;878(25):2362-2353.