Detection of ketosis in dairy cows by analysis of exhaled breath

P Dobbelaar; T Mottram; C Nyabadza; P Hobbs; R J Elliott-Martin; Y H Schukken

doi:10.1080/01652176.1996.9694638

Detection of ketosis in dairy cows by analysis of exhaled breath

P Dobbelaar, T Mottram, C Nyabadza, P Hobbs, R J Elliott-Martin, Y H Schukken

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In four healthy cows an elevation of ketone bodies was induced by reduction of feed intake. Two cows became clearly ketotic while the other two cows showed only slight increases in ketone body concentrations in serum and milk. Acetone concentrations in exhaled breath were measured by gas chromatography combined with mass spectrometry. These values were correlated with concentrations of serum beta-hydroxybutyric acid (r = 0.81) and milk acetoacetate+acetone (r = 0.70). It is concluded that the ketotic state of dairy cows can be detected by analysis of exhaled breath. This offers a potential non-invasive method of determining the metabolic state of dairy cows.

Original language	English
Pages (from-to)	151-2
Number of pages	2
Journal	The Veterinary quarterly
Volume	18
Issue number	4
DOIs	https://doi.org/10.1080/01652176.1996.9694638
Publication status	Published - Dec 1996

Keywords

3-Hydroxybutyric Acid
Acetone/analysis
Animals
Breath Tests/methods
Cattle/metabolism
Cattle Diseases/diagnosis
Chromatography, Gas/veterinary
Female
Gas Chromatography-Mass Spectrometry/veterinary
Hydroxybutyrates/blood
Ketone Bodies/analysis
Ketosis/diagnosis
Milk/chemistry

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10.1080/01652176.1996.9694638

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title = "Detection of ketosis in dairy cows by analysis of exhaled breath",

abstract = "In four healthy cows an elevation of ketone bodies was induced by reduction of feed intake. Two cows became clearly ketotic while the other two cows showed only slight increases in ketone body concentrations in serum and milk. Acetone concentrations in exhaled breath were measured by gas chromatography combined with mass spectrometry. These values were correlated with concentrations of serum beta-hydroxybutyric acid (r = 0.81) and milk acetoacetate+acetone (r = 0.70). It is concluded that the ketotic state of dairy cows can be detected by analysis of exhaled breath. This offers a potential non-invasive method of determining the metabolic state of dairy cows.",

keywords = "3-Hydroxybutyric Acid, Acetone/analysis, Animals, Breath Tests/methods, Cattle/metabolism, Cattle Diseases/diagnosis, Chromatography, Gas/veterinary, Female, Gas Chromatography-Mass Spectrometry/veterinary, Hydroxybutyrates/blood, Ketone Bodies/analysis, Ketosis/diagnosis, Milk/chemistry",

author = "P Dobbelaar and T Mottram and C Nyabadza and P Hobbs and Elliott-Martin, {R J} and Schukken, {Y H}",

year = "1996",

month = dec,

doi = "10.1080/01652176.1996.9694638",

language = "English",

volume = "18",

pages = "151--2",

journal = "The Veterinary quarterly",

issn = "0165-2176",

publisher = "Taylor and Francis Ltd.",

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TY - JOUR

T1 - Detection of ketosis in dairy cows by analysis of exhaled breath

AU - Dobbelaar, P

AU - Mottram, T

AU - Nyabadza, C

AU - Hobbs, P

AU - Elliott-Martin, R J

AU - Schukken, Y H

PY - 1996/12

Y1 - 1996/12

N2 - In four healthy cows an elevation of ketone bodies was induced by reduction of feed intake. Two cows became clearly ketotic while the other two cows showed only slight increases in ketone body concentrations in serum and milk. Acetone concentrations in exhaled breath were measured by gas chromatography combined with mass spectrometry. These values were correlated with concentrations of serum beta-hydroxybutyric acid (r = 0.81) and milk acetoacetate+acetone (r = 0.70). It is concluded that the ketotic state of dairy cows can be detected by analysis of exhaled breath. This offers a potential non-invasive method of determining the metabolic state of dairy cows.

AB - In four healthy cows an elevation of ketone bodies was induced by reduction of feed intake. Two cows became clearly ketotic while the other two cows showed only slight increases in ketone body concentrations in serum and milk. Acetone concentrations in exhaled breath were measured by gas chromatography combined with mass spectrometry. These values were correlated with concentrations of serum beta-hydroxybutyric acid (r = 0.81) and milk acetoacetate+acetone (r = 0.70). It is concluded that the ketotic state of dairy cows can be detected by analysis of exhaled breath. This offers a potential non-invasive method of determining the metabolic state of dairy cows.

KW - 3-Hydroxybutyric Acid

KW - Acetone/analysis

KW - Animals

KW - Breath Tests/methods

KW - Cattle/metabolism

KW - Cattle Diseases/diagnosis

KW - Chromatography, Gas/veterinary

KW - Female

KW - Gas Chromatography-Mass Spectrometry/veterinary

KW - Hydroxybutyrates/blood

KW - Ketone Bodies/analysis

KW - Ketosis/diagnosis

KW - Milk/chemistry

U2 - 10.1080/01652176.1996.9694638

DO - 10.1080/01652176.1996.9694638

M3 - Article

C2 - 8972064

SN - 0165-2176

VL - 18

SP - 151

EP - 152

JO - The Veterinary quarterly

JF - The Veterinary quarterly

IS - 4

ER -

Detection of ketosis in dairy cows by analysis of exhaled breath

Abstract

Keywords

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