Detection of bacterial DNA in bile of cats with lymphocytic cholangitis

C. Otte, O.P. Gutiérrez, R.P. Favier, J. Rothuizen, L.C. Penning

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    AbstractIn this study, we have successfully used molecular methods based on the amplification of the 16S ribosomal RNA gene on feline bile samples to show that bile of cats with LC is not sterile. This is probably due to the fact that the inflammatory process in the biliary tree causes dilatations. As a result, bacteria can easily migrate from the intestines via the common bile duct. The diversity of species identified and the presence of Helicobacter spp. DNA in both patients and controls suggests that bacteriobilia is secondary to the disease and is not the cause of LC.
    Original languageEnglish
    Pages (from-to)217-221
    Number of pages5
    JournalVeterinary Microbiology
    Volume156
    Issue number1-2
    DOIs
    Publication statusPublished - 2012

    Keywords

    • Cats
    • Hepatobiliary disease
    • Helicobacter spp.
    • DGGE
    • 16s rDNA

    Fingerprint

    Dive into the research topics of 'Detection of bacterial DNA in bile of cats with lymphocytic cholangitis'. Together they form a unique fingerprint.

    Cite this