Detailed mechanistic insights into HIV-1 sensitivity to three generations of fusion inhibitors

Keyphrases

• Human Immunodeficiency Virus Type 1 (HIV-1) 100%
• Mechanistic Insight 100%
• Fusion Inhibitor 100%
• Three-generation 100%
• Mutational Analysis 33%
• Heptad Repeat 33%
• Viral 33%
• Amino Acid Substitution 33%
• Peptide Inhibitor 33%
• Virus Entry 33%
• Class I Fusion Protein 33%
• Peptide-based 33%
• Electrostatic Force 33%
• Novel Antivirals 33%
• Peptide Binding Site 33%
• Electrostatic Repulsion 33%
• Third Generation 33%
• Drug Resistance Mechanisms 33%
• Inhibitor Resistance 33%
• Enfuvirtide 33%
• Charged Amino Acids 33%
• Antiviral Peptides 33%
• Inhibitor Potency 33%

Pharmacology, Toxicology and Pharmaceutical Science

• HIV 100%
• Human Immunodeficiency Virus Fusion Inhibitor 100%
• Enfuvirtide 100%
• Tifuvirtide 40%
• Amino Acid 40%
• Antivirus Agent 20%
• Obstruction 20%
• Binding Site 20%
• Chimeric Protein 20%
• Human Immunodeficiency Virus 1 20%
• Drug Resistance 20%

Biochemistry, Genetics and Molecular Biology

• Human Immunodeficiency Virus 1 100%
• Enfuvirtide 100%
• Heptad Repeat 20%
• Amino Acids 20%
• Binding Site 20%
• Virus Entry 20%
• Amino Acid Substitution 20%
• Drug Resistance 20%
• Chimeric Protein 20%