Depression, Anxiety, and Stress among Hangover-Sensitive and Hangover-Resistant Drinkers

  • Andy J Kim
  • , Agnese Merlo
  • , Marlou Mackus
  • , Gillian Bruce
  • , Sean J Johnson
  • , Chris Alford
  • , Simon B Sherry
  • , Sherry H Stewart
  • , Joris C Verster*
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

This study investigated potential differences in baseline (i.e., non-hangover-related) levels of depression, anxiety, and stress between individuals who are sensitive to and those resistant to hangovers after consuming alcohol. Participants included 5111 university students from the Netherlands and the U.K., including 3205 hangover-sensitive and 1906 hangover-resistant drinkers. All participants completed surveys on their demographics, alcohol consumption, and hangover susceptibility (whether they experienced a hangover in the past 12 months), as well as their baseline levels of depression, anxiety, and stress on the DASS-21 scale. The results showed that hangover-sensitive drinkers had significantly higher levels of anxiety and stress, but not depression, compared to hangover-resistant drinkers. However, the observed differences between the two groups were small, with a magnitude of less than 1 out of 42 points on the DASS-21 anxiety and stress subscales, and are thus unlikely to be clinically meaningful.

Original languageEnglish
Article number2766
JournalJournal of Clinical Medicine
Volume12
Issue number8
DOIs
Publication statusPublished - 7 Apr 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Funding

Over the past three years, J.C.V. has acted as a consultant/advisor for Eisai, KNMP, Red Bull, Sen-Jam Pharmaceutical, and Toast! C.A. has undertaken sponsored research, or provided consultancy, for a number of companies and organizations including Airbus Group Industries, Astra, British Aerospace/BAE Systems, the UK Civil Aviation Authority, Duphar, Farm Italia, Carlo Erba, Ford Motor Company, ICI, Innovate UK, Janssen, LERS Synthélabo, Lilly, Lorex/Searle, the UK Ministry of Defence, More Labs, Quest International, Red Bull GmbH, Rhone-Poulenc Rorer, Sanofi Aventis, and Vital Beverages. S.J.J. has undertaken sponsored research for Pfizer, AstraZeneca, Merck, Gilead, Novartis, Roche, Red Bull GmbH, the Department for Transport, and Road Safety Trust. S.H.S. has been a consultant to Beer Canada, received funding from the Alcoholic Beverage Medical Research Foundation, and is supported through a Tier 1 Canada Research Chair in Addictions and Mental Health at Dalhousie University. The other authors have no potential conflicts of interest to disclose.

Funders
Alcoholic Beverage Medical Research Foundation
Universiteit Utrecht
Dalhousie University
Descartes Centre voor Wetenschapsgeschiedenis en Wetenschapsfilosofie, Universiteit Utrecht

    Keywords

    • alcohol
    • anxiety
    • depression
    • hangover
    • resistance
    • stress

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