Deep sequencing of prostasomal RNA

Carla Zijlstra, Willem Stoorvogel

    Research output: Contribution to conferencePosterOther research output

    Abstract

    Prostasomes are extracellular vesicles that are released by the epithelial cells of the prostate gland and secreted into the seminal fluid. Their proposed roles include regulation of sperm cell function and immune suppression to prevent destruction of sperm cells in the female reproductive tract. Prostasomes that are released by hyperplastic, malignant and metastatic prostate tumor cells display characteristics similar to those of normal cells but may also contain tumor specific molecular content. Prostate tumor cells may release prostasomes into the interstitial compartment or even into the blood circulation. Therefore, the presence of prostasome specific markers in the blood might be indicative for prostate cancer. To identify potential prostasome specific markers, we analyzed the RNA content of prostasomes derived from healthy vasectomized men
    Original languageEnglish
    Publication statusPublished - 2014
    EventISEV meeting - Gothenburg, Sweden
    Duration: 18 Jan 2012 → …

    Other

    OtherISEV meeting
    CityGothenburg, Sweden
    Period18/01/12 → …

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