De novo generation of a functional human thymus from induced pluripotent stem cells

Amiet R Chhatta; Martijn Cordes; Maaike A J Hanegraaf; Sandra Vloemans; Tom Cupedo; Jan J Cornelissen; Francoise Carlotti; Daniela Salvatori; Karin Pike-Overzet; Willem E Fibbe; Rob C Hoeben; Harald M M Mikkers; Frank J T Staal

doi:10.1016/j.jaci.2019.05.042

De novo generation of a functional human thymus from induced pluripotent stem cells

Amiet R Chhatta, Martijn Cordes, Maaike A J Hanegraaf, Sandra Vloemans, Tom Cupedo, Jan J Cornelissen, Francoise Carlotti, Daniela Salvatori, Karin Pike-Overzet, Willem E Fibbe, Rob C Hoeben, Harald M M Mikkers, Frank J T Staal

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1416-1419.e7
Journal	Journal of Allergy and Clinical Immunology
Volume	144
Issue number	5
Early online date	16 Jul 2019
DOIs	https://doi.org/10.1016/j.jaci.2019.05.042
Publication status	Published - 5 Nov 2019
Externally published	Yes

Keywords

Animals
Cell Differentiation
Cells, Cultured
Forkhead Transcription Factors/genetics
Humans
Induced Pluripotent Stem Cells/physiology
Mice
Mice, Knockout
Mice, Nude
Morphogenesis
Organ Culture Techniques
Organ Transplantation
Thymus Gland/physiology
Transplantation, Heterologous

Access to Document

10.1016/j.jaci.2019.05.042

Cite this

Chhatta, A. R., Cordes, M., Hanegraaf, M. A. J., Vloemans, S., Cupedo, T., Cornelissen, J. J., Carlotti, F., Salvatori, D., Pike-Overzet, K., Fibbe, W. E., Hoeben, R. C., Mikkers, H. M. M., & Staal, F. J. T. (2019). De novo generation of a functional human thymus from induced pluripotent stem cells. Journal of Allergy and Clinical Immunology, 144(5), 1416-1419.e7. https://doi.org/10.1016/j.jaci.2019.05.042

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title = "De novo generation of a functional human thymus from induced pluripotent stem cells",

keywords = "Animals, Cell Differentiation, Cells, Cultured, Forkhead Transcription Factors/genetics, Humans, Induced Pluripotent Stem Cells/physiology, Mice, Mice, Knockout, Mice, Nude, Morphogenesis, Organ Culture Techniques, Organ Transplantation, Thymus Gland/physiology, Transplantation, Heterologous",

author = "Chhatta, {Amiet R} and Martijn Cordes and Hanegraaf, {Maaike A J} and Sandra Vloemans and Tom Cupedo and Cornelissen, {Jan J} and Francoise Carlotti and Daniela Salvatori and Karin Pike-Overzet and Fibbe, {Willem E} and Hoeben, {Rob C} and Mikkers, {Harald M M} and Staal, {Frank J T}",

year = "2019",

month = nov,

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doi = "10.1016/j.jaci.2019.05.042",

language = "English",

volume = "144",

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Chhatta, AR, Cordes, M, Hanegraaf, MAJ, Vloemans, S, Cupedo, T, Cornelissen, JJ, Carlotti, F, Salvatori, D, Pike-Overzet, K, Fibbe, WE, Hoeben, RC, Mikkers, HMM & Staal, FJT 2019, 'De novo generation of a functional human thymus from induced pluripotent stem cells', Journal of Allergy and Clinical Immunology, vol. 144, no. 5, pp. 1416-1419.e7. https://doi.org/10.1016/j.jaci.2019.05.042

TY - JOUR

T1 - De novo generation of a functional human thymus from induced pluripotent stem cells

AU - Chhatta, Amiet R

AU - Cordes, Martijn

AU - Hanegraaf, Maaike A J

AU - Vloemans, Sandra

AU - Cupedo, Tom

AU - Cornelissen, Jan J

AU - Carlotti, Francoise

AU - Salvatori, Daniela

AU - Pike-Overzet, Karin

AU - Fibbe, Willem E

AU - Hoeben, Rob C

AU - Mikkers, Harald M M

AU - Staal, Frank J T

PY - 2019/11/5

Y1 - 2019/11/5

KW - Animals

KW - Cell Differentiation

KW - Cells, Cultured

KW - Forkhead Transcription Factors/genetics

KW - Humans

KW - Induced Pluripotent Stem Cells/physiology

KW - Mice

KW - Mice, Knockout

KW - Mice, Nude

KW - Morphogenesis

KW - Organ Culture Techniques

KW - Organ Transplantation

KW - Thymus Gland/physiology

KW - Transplantation, Heterologous

U2 - 10.1016/j.jaci.2019.05.042

DO - 10.1016/j.jaci.2019.05.042

M3 - Article

C2 - 31323248

SN - 0091-6749

VL - 144

SP - 1416-1419.e7

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 5

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