Construction of Adjacent Quaternary and Tertiary Stereocenters via an Organocatalytic Allylic Alkylation of Morita-Baylis-Hillman Carbonates

D.J.V.C. van Steenis, T. Marcelli, M. Lutz, A.L. Spek, J.H. van Maarseveen, H. Hiemstra

Research output: Contribution to journalArticleAcademicpeer-review


Racemic Baylis-Hillman carbonates can be converted in densely functionalized products by reaction with cyano esters in the presence of a catalytic amount of a modified Cinchona alkaloid in high enantioselectivities and fair diastereoselectivities. A rational for the observed stereoselectivity is presented
Original languageUndefined/Unknown
Pages (from-to)281-286
Number of pages6
JournalAdvanced synthesis & catalysis
Issue number3
Publication statusPublished - 2007

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