Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Ellen Fritsche, Philippe Grandjean, Kevin M Crofton, Michael Aschner, Alan Goldberg, Tuula Heinonen, Ellen V S Hessel, Helena T Hogberg, Susanne Hougaard Bennekou, Pamela J Lein, Marcel Leist, William R Mundy, Martin Paparella, Aldert H Piersma, Magdalini Sachana, Gabriele Schmuck, Roland Solecki, Andrea Terron, Florianne Monnet-Tschudi, Martin F WilksHilda Witters, Marie-Gabrielle Zurich, Anna Bal-Price

IUF - Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany.
University of Southern Denmark, Harvard T.H. Chan School of Public Health, USA.
Neurotoxicologist, Durham, NC, USA.
Albert Einstein College of Medicine Bronx, New York, USA.
Bloomberg School of Public Health, Founding Director (Emeritus) of Center for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, USA; Global Food Ethics, Johns Hopkins University, Baltimore, USA.
Finnish Centre for Alternative Methods (FICAM), University of Tampere, Tampere, Finland.
National Institute for Public Health and the Environment, RIVM Center for Health Protection, Bilthoven, Netherlands.
Centre for Alternatives to Animal Testing (CAAT), Johns Hopkins University, Baltimore, USA.
The Danish Environmental Protection Agency (EPA), Copenhagen, Denmark.
Department of Molecular Biosciences, School of Veterinary Medicine, University of California Davis, Davis, USA.
CAAT - Centre for Alternatives to Animal Testing, University of Konstanz, Konstanz, Germany.
Neurotoxicologist, Durham, USA.
Austrian National Coordinator of Testing Methods, Austria.
RIVM Center for Health Protection, Bilthoven and Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
Organisation for Economic Co-operation and Development (OECD), Paris, France.
Bayer, Wuppertal, Germany.
Federal Institute for Risk Assessment (BfR), Berlin, Germany.
European Food Safety Authority (EFSA), Parma, Italy.
Department of Physiology, University of Lausanne and SCAHT, Switzerland.
SCAHT - Swiss Centre for Applied Human Toxicology, University of Basel, Basel, Switzerland.
Environmental Risk and Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium.
European Commission -DG Joint Research Centre (JRC), Ispra, Italy. Electronic address: [email protected].

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Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

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Keyphrases

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science