TY - JOUR
T1 - Computer-Assisted Assignment of Homonuclear 3D NMR Spectra of Proteins. Application to Pike Parvalbumin III
AU - Kleywegt, Gerard J.
AU - Vuister, Geerten W.
AU - Padilla, André
AU - Knegtel, Ronald M.A.
AU - Boelens, Rolf
AU - Kaptein, Robert
PY - 1993
Y1 - 1993
N2 - We have developed algorithms for semiautomatic assignment of homonuclear [1H, 1H, 1H] 3D [J, NOE]- and [NOE, J]-type NMR spectra of proteins. The potential of these algorithms is demonstrated on a peak-picked 3D Clean TOCSY-NOE spectrum of pike parvalbumin III. The algorithms have been embedded in a computer program called ALISON, which provides general display, bookkeeping, and assignment tools for the analysis of homonuclear and heteronuclear 3D NMR spectra of biomacromolecules.
AB - We have developed algorithms for semiautomatic assignment of homonuclear [1H, 1H, 1H] 3D [J, NOE]- and [NOE, J]-type NMR spectra of proteins. The potential of these algorithms is demonstrated on a peak-picked 3D Clean TOCSY-NOE spectrum of pike parvalbumin III. The algorithms have been embedded in a computer program called ALISON, which provides general display, bookkeeping, and assignment tools for the analysis of homonuclear and heteronuclear 3D NMR spectra of biomacromolecules.
UR - http://www.scopus.com/inward/record.url?scp=0001360451&partnerID=8YFLogxK
U2 - 10.1006/jmrb.1993.1079
DO - 10.1006/jmrb.1993.1079
M3 - Article
AN - SCOPUS:0001360451
SN - 1064-1866
VL - 102
SP - 166
EP - 176
JO - Journal of Magnetic Resonance, Series B
JF - Journal of Magnetic Resonance, Series B
IS - 2
ER -