Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques

Keyphrases

• Complement Receptors 100%
• Atherosclerotic Plaque 100%
• Receptor Targets 100%
• Targeted Liposomes 100%
• Liver X Receptor 100%
• AZD3965 100%
• Liposomes 85%
• Foam Cells 57%
• Plaque 28%
• Plasma Lipids 28%
• Plaque Macrophages 28%
• Clinical Development 14%
• Long-term Treatment 14%
• Lipids 14%
• Therapeutic Agents 14%
• Flow Cytometric Analysis 14%
• Macrophages 14%
• Receptor Activation 14%
• Lipid Content 14%
• Lipid Levels 14%
• High Accumulation 14%
• Cyclic Peptide 14%
• Low-density Lipoprotein Receptor 14%
• Atherosclerotic Lesions 14%
• Hepatic Lipid 14%
• In Vivo Imaging 14%
• Macrophage Content 14%
• Liver Lipid 14%
• Plaque Stabilization 14%
• Arterial Intima 14%
• Reverse Cholesterol Transport 14%
• Preferential Uptake 14%

Biochemistry, Genetics and Molecular Biology

• Receptor Agonists 100%
• Complement Receptor 100%
• Liver X Receptor 100%
• Foam Cell 100%
• Macrophage 75%
• Blood Lipids 50%
• Lipid 25%
• Reverse Cholesterol Transport 25%
• Lipid Liver Level 25%
• Lipid Level 25%
• Low Density Lipoprotein Receptor Knockout Mouse 25%
• Flow Cytometry 25%
• Cyclic Peptide 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Liposome 100%
• Complement Receptor 100%
• Liver X Receptor Agonist 100%
• 3 [3 [[2 Chloro 3 (Trifluoromethyl)benzyl](2 Diphenylethyl)amino]propoxy]phenylacetic Acid 100%
• Flow Cytometry 12%
• Low Density Lipoprotein Receptor Knockout Mouse 12%
• Side Effect 12%
• Receptor 12%
• Cyclopeptide 12%
• Atherosclerosis 12%
• Phosphorus 32 12%
• Liver X Receptor 12%