Comparative studies on prognostic markers and signaling pathways for canine and human osteosarcoma

G.T. Selvarajah

Comparative studies on prognostic markers and signaling pathways for canine and human osteosarcoma

G.T. Selvarajah

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

Abstract

Osteosarcoma is an aggressive bone tumor that occurs naturally mainly in large and medium breed dogs where almost 90% of dogs will develop metastasis predominantly in the lungs. The standard treatments (extirpation of the primary tumor including limb amputation/sparing, post-operative chemotherapy and palliative radiotherapy) have increased survival rates as compared to denying options for therapy upon diagnosis. Despite the advances in various therapies, prognosis remains poor, with

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	Utrecht University
Supervisors/Advisors	Kirpensteijn, J., Primary supervisor Mol, J.A., Co-supervisor Kik, Marja, Co-supervisor
Award date	29 Mar 2011
Print ISBNs	978-90-393-5527-5
Publication status	Published - 29 Mar 2011

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abstract = "Osteosarcoma is an aggressive bone tumor that occurs naturally mainly in large and medium breed dogs where almost 90% of dogs will develop metastasis predominantly in the lungs. The standard treatments (extirpation of the primary tumor including limb amputation/sparing, post-operative chemotherapy and palliative radiotherapy) have increased survival rates as compared to denying options for therapy upon diagnosis. Despite the advances in various therapies, prognosis remains poor, with",

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AB - Osteosarcoma is an aggressive bone tumor that occurs naturally mainly in large and medium breed dogs where almost 90% of dogs will develop metastasis predominantly in the lungs. The standard treatments (extirpation of the primary tumor including limb amputation/sparing, post-operative chemotherapy and palliative radiotherapy) have increased survival rates as compared to denying options for therapy upon diagnosis. Despite the advances in various therapies, prognosis remains poor, with

M3 - Doctoral thesis 1 (Research UU / Graduation UU)

SN - 978-90-393-5527-5

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Comparative studies on prognostic markers and signaling pathways for canine and human osteosarcoma

Abstract

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