Cognitive therapy and interpersonal psychotherapy reduce suicidal ideation independent from their effect on depression

J.S. van Bentum; S.C. van Bronswijk; M. Sijbrandij; L.H.J.M. Lemmens; F.F.P.M.L. Peeters; M. Drukker; M.J.H. Huibers

doi:10.1002/da.23151

Cognitive therapy and interpersonal psychotherapy reduce suicidal ideation independent from their effect on depression

J.S. van Bentum^*, S.C. van Bronswijk, M. Sijbrandij, L.H.J.M. Lemmens, F.F.P.M.L. Peeters, M. Drukker, M.J.H. Huibers

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: Clinical guidelines suggest that psychological interventions specifically aimed at reducing suicidality may be beneficial. We examined the impact of two depression treatments, cognitive therapy (CT) and interpersonal psychotherapy (IPT) on suicidal ideation (SI) and explored the temporal associations between depression and SI over the course of therapy.

Methods: Ninety-one adult (18–65) depressed outpatients from a large randomized controlled trial who were treated with CT (n = 37) and IPT (n = 54) and scored at least ≥1 on the Beck Depression Inventory II (BDI-II) suicide item were included. Linear (two-level) mixed effects models were used to evaluate the impact of depression treatments on SI. Mixed-effects time-lagged models were applied to examine temporal relations between the change in depressive symptoms and the change in SI.

Results: SI decreased significantly during treatment and there were no differential effects between the two intervention groups (B = −0.007, p =.35). Depressive symptoms at the previous session did not predict higher levels of SI at the current session (B = 0.016, p =.16). However, SI measured at the previous session significantly predicted depressive symptoms at the current session (B = 2.06, p <.001).

Conclusions: Both depression treatments seemed to have a direct association with SI. The temporal association between SI and depression was unidirectional with SI predicting future depressive symptoms during treatment. Our findings suggest that it may be most beneficial to treat SI first.

Original language	English
Pages (from-to)	940-949
Journal	Depression and Anxiety
Volume	38
Issue number	9
DOIs	https://doi.org/10.1002/da.23151
Publication status	Published - 2021
Externally published	Yes

Bibliographical note

Funding Information:
The authors wish to acknowledge the contribution of participating patients and therapists at RIAGG Maastricht. Furthermore, we thank Annie Raven and Annie Hendriks for their assistance during the study. This study was funded by the Research Institute of Experimental Psychopathology (EPP), the Netherlands, and the Academic Community Mental Health Centre (RIAGG) in Maastricht, the Netherlands.

Publisher Copyright:
© 2021 The Authors. Depression and Anxiety published by Wiley Periodicals LLC

Funding

The authors wish to acknowledge the contribution of participating patients and therapists at RIAGG Maastricht. Furthermore, we thank Annie Raven and Annie Hendriks for their assistance during the study. This study was funded by the Research Institute of Experimental Psychopathology (EPP), the Netherlands, and the Academic Community Mental Health Centre (RIAGG) in Maastricht, the Netherlands.

Keywords

adult
cognitive behavioral therapy
depression
interpersonal psychotherapy
linear models
randomized controlled trial
suicide

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Depression and Anxiety - 2021 - Bentum - Cognitive therapy and interpersonal psychotherapy reduce suicidal ideationFinal published version, 796 KBLicence: CC BY

Cite this

@article{be799fd646a4483280acf5408c4053c7,

title = "Cognitive therapy and interpersonal psychotherapy reduce suicidal ideation independent from their effect on depression",

abstract = "Background: Clinical guidelines suggest that psychological interventions specifically aimed at reducing suicidality may be beneficial. We examined the impact of two depression treatments, cognitive therapy (CT) and interpersonal psychotherapy (IPT) on suicidal ideation (SI) and explored the temporal associations between depression and SI over the course of therapy. Methods: Ninety-one adult (18–65) depressed outpatients from a large randomized controlled trial who were treated with CT (n = 37) and IPT (n = 54) and scored at least ≥1 on the Beck Depression Inventory II (BDI-II) suicide item were included. Linear (two-level) mixed effects models were used to evaluate the impact of depression treatments on SI. Mixed-effects time-lagged models were applied to examine temporal relations between the change in depressive symptoms and the change in SI. Results: SI decreased significantly during treatment and there were no differential effects between the two intervention groups (B = −0.007, p =.35). Depressive symptoms at the previous session did not predict higher levels of SI at the current session (B = 0.016, p =.16). However, SI measured at the previous session significantly predicted depressive symptoms at the current session (B = 2.06, p <.001). Conclusions: Both depression treatments seemed to have a direct association with SI. The temporal association between SI and depression was unidirectional with SI predicting future depressive symptoms during treatment. Our findings suggest that it may be most beneficial to treat SI first.",

keywords = "adult, cognitive behavioral therapy, depression, interpersonal psychotherapy, linear models, randomized controlled trial, suicide",

author = "{van Bentum}, J.S. and {van Bronswijk}, S.C. and M. Sijbrandij and L.H.J.M. Lemmens and F.F.P.M.L. Peeters and M. Drukker and M.J.H. Huibers",

note = "Funding Information: The authors wish to acknowledge the contribution of participating patients and therapists at RIAGG Maastricht. Furthermore, we thank Annie Raven and Annie Hendriks for their assistance during the study. This study was funded by the Research Institute of Experimental Psychopathology (EPP), the Netherlands, and the Academic Community Mental Health Centre (RIAGG) in Maastricht, the Netherlands. Publisher Copyright: {\textcopyright} 2021 The Authors. Depression and Anxiety published by Wiley Periodicals LLC",

year = "2021",

doi = "10.1002/da.23151",

language = "English",

volume = "38",

pages = "940--949",

journal = "Depression and Anxiety",

issn = "1091-4269",

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TY - JOUR

T1 - Cognitive therapy and interpersonal psychotherapy reduce suicidal ideation independent from their effect on depression

AU - van Bentum, J.S.

AU - van Bronswijk, S.C.

AU - Sijbrandij, M.

AU - Lemmens, L.H.J.M.

AU - Peeters, F.F.P.M.L.

AU - Drukker, M.

AU - Huibers, M.J.H.

N1 - Funding Information: The authors wish to acknowledge the contribution of participating patients and therapists at RIAGG Maastricht. Furthermore, we thank Annie Raven and Annie Hendriks for their assistance during the study. This study was funded by the Research Institute of Experimental Psychopathology (EPP), the Netherlands, and the Academic Community Mental Health Centre (RIAGG) in Maastricht, the Netherlands. Publisher Copyright: © 2021 The Authors. Depression and Anxiety published by Wiley Periodicals LLC

PY - 2021

Y1 - 2021

N2 - Background: Clinical guidelines suggest that psychological interventions specifically aimed at reducing suicidality may be beneficial. We examined the impact of two depression treatments, cognitive therapy (CT) and interpersonal psychotherapy (IPT) on suicidal ideation (SI) and explored the temporal associations between depression and SI over the course of therapy. Methods: Ninety-one adult (18–65) depressed outpatients from a large randomized controlled trial who were treated with CT (n = 37) and IPT (n = 54) and scored at least ≥1 on the Beck Depression Inventory II (BDI-II) suicide item were included. Linear (two-level) mixed effects models were used to evaluate the impact of depression treatments on SI. Mixed-effects time-lagged models were applied to examine temporal relations between the change in depressive symptoms and the change in SI. Results: SI decreased significantly during treatment and there were no differential effects between the two intervention groups (B = −0.007, p =.35). Depressive symptoms at the previous session did not predict higher levels of SI at the current session (B = 0.016, p =.16). However, SI measured at the previous session significantly predicted depressive symptoms at the current session (B = 2.06, p <.001). Conclusions: Both depression treatments seemed to have a direct association with SI. The temporal association between SI and depression was unidirectional with SI predicting future depressive symptoms during treatment. Our findings suggest that it may be most beneficial to treat SI first.

AB - Background: Clinical guidelines suggest that psychological interventions specifically aimed at reducing suicidality may be beneficial. We examined the impact of two depression treatments, cognitive therapy (CT) and interpersonal psychotherapy (IPT) on suicidal ideation (SI) and explored the temporal associations between depression and SI over the course of therapy. Methods: Ninety-one adult (18–65) depressed outpatients from a large randomized controlled trial who were treated with CT (n = 37) and IPT (n = 54) and scored at least ≥1 on the Beck Depression Inventory II (BDI-II) suicide item were included. Linear (two-level) mixed effects models were used to evaluate the impact of depression treatments on SI. Mixed-effects time-lagged models were applied to examine temporal relations between the change in depressive symptoms and the change in SI. Results: SI decreased significantly during treatment and there were no differential effects between the two intervention groups (B = −0.007, p =.35). Depressive symptoms at the previous session did not predict higher levels of SI at the current session (B = 0.016, p =.16). However, SI measured at the previous session significantly predicted depressive symptoms at the current session (B = 2.06, p <.001). Conclusions: Both depression treatments seemed to have a direct association with SI. The temporal association between SI and depression was unidirectional with SI predicting future depressive symptoms during treatment. Our findings suggest that it may be most beneficial to treat SI first.

KW - adult

KW - cognitive behavioral therapy

KW - depression

KW - interpersonal psychotherapy

KW - linear models

KW - randomized controlled trial

KW - suicide

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DO - 10.1002/da.23151

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AN - SCOPUS:85102878122

SN - 1091-4269

VL - 38

SP - 940

EP - 949

JO - Depression and Anxiety

JF - Depression and Anxiety

IS - 9

ER -

Cognitive therapy and interpersonal psychotherapy reduce suicidal ideation independent from their effect on depression

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

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