TY - JOUR
T1 - Characterization of a periplasmic protein involved in iron utilization of Actinobacillus actinomycetemcomitans
AU - Willemsen, P. T.
AU - Vulto, I.
AU - Boxem, M.
AU - De Graaff, J.
PY - 1997
Y1 - 1997
N2 - The periodontopathic bacterium Actinobacillus actinomycetemcomitans possesses a 35-kDa periplasmic iron-repressible protein. Its regulation is mediated by the Fur protein, as was inferred from the Fur-binding consensus sequence at the -35 position of the gene for the 35-kDa protein and from the relaxed expression of the gene in a mutant with an altered Fur-binding sequence. The 35-kDa protein, designated AfuA, has strong homology to HitA and FbpA of Haemophilus influenzae and Neisseria meningitidis, respectively, which serve as periplasmic iron transport proteins.
AB - The periodontopathic bacterium Actinobacillus actinomycetemcomitans possesses a 35-kDa periplasmic iron-repressible protein. Its regulation is mediated by the Fur protein, as was inferred from the Fur-binding consensus sequence at the -35 position of the gene for the 35-kDa protein and from the relaxed expression of the gene in a mutant with an altered Fur-binding sequence. The 35-kDa protein, designated AfuA, has strong homology to HitA and FbpA of Haemophilus influenzae and Neisseria meningitidis, respectively, which serve as periplasmic iron transport proteins.
UR - http://www.scopus.com/inward/record.url?scp=0030818713&partnerID=8YFLogxK
U2 - 10.1128/jb.179.15.4949-4952.1997
DO - 10.1128/jb.179.15.4949-4952.1997
M3 - Article
C2 - 9244288
AN - SCOPUS:0030818713
SN - 0021-9193
VL - 179
SP - 4949
EP - 4952
JO - Journal of Bacteriology
JF - Journal of Bacteriology
IS - 15
ER -