Chapter 9: Environmental an occupational toxicants

F. de Vocht, J.J. Vlaanderen, A.C. Povey, S. Balbo, R. Vermeulen

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

    Abstract

    Biological monitoring is the analysis of human biological materials for a substance of interest and/or its metabolites (biomarkers) or a biochemical change that occurs as a result of an exposure to provide a quantitative measure of exposure or dose. These measures can be used in epidemiological studies either directly as estimates of exposure or indirectly in the calibration of other exposure assessment methods, such as questionnaires. This chapter will discuss important methodological considerations for the implementation of biomarkers of exogenous exposure in epidemiology by focusing on biomarker characteristics (e.g. variability, half-life) and their application in different study designs.
    Original languageEnglish
    Title of host publicationMolecular Epidemiology: Pinciples and Practices
    EditorsN. Rothman, P. Hainaut, P. Schulte, M. Smith, P. Boffetta, F. Perera
    Place of PublicationGeneva, Switzerland
    PublisherWHO Press
    Pages163-174
    Number of pages12
    ISBN (Print)9789283221630
    Publication statusPublished - 2012

    Publication series

    NameIARC scientific publications
    Number163

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