Cancer stem cells: where do they come from and where are they going?

Christine L. Mummery, Anja van de Stolpe, Bernard Roelen, Hans Clevers

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Cancer is a diagnosis still widely feared despite recent developments in excellent treatments and even cures for many types. Understanding cancer stem cells may lead to new ways to tackle the disease. We discuss these very unusual cells in this chapter.
Original languageEnglish
Title of host publicationStem Cells
Subtitle of host publicationScientific Facts and Fiction
EditorsChristine L. Mummery, Anja van de Stolpe, Bernard Roelen, Hans Clevers
PublisherAcademic Press
Chapter12
Pages299-328
Number of pages30
Edition3
ISBN (Print)978-0-12-820337-8
DOIs
Publication statusPublished - 2021

Keywords

  • Tumor
  • intestinal crypt
  • signaling pathway
  • Wnt
  • mutation
  • malignant
  • niche
  • EMT

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