Cancer-ID: towards identification of cancer by tumor-derived extracellular vesicles in blood

L G Rikkert; P Beekman; J Caro; F A W Coumans; A Enciso Martinez; G Jenster; S Le Gac; W Lee; Ton G Van Leeuwen; G B Loozen; A Nanou; R Nieuwland; H L Offerhaus; C Otto; D M Pegtel; M C Piontek; E Van Der Pol; L De Rond; W H Roos; R B M Schasfoort; Marca Wauben; H Zuilhof; Leon WMM Terstappen

doi:10.3389/FONC.2020.00608

Cancer-ID: towards identification of cancer by tumor-derived extracellular vesicles in blood

L G Rikkert
, P Beekman
, J Caro
, F A W Coumans
, A Enciso Martinez
, G Jenster
, S Le Gac
, W Lee
, Ton G Van Leeuwen
, G B Loozen
, A Nanou
, R Nieuwland
, H L Offerhaus
, C Otto
, D M Pegtel
, M C Piontek
, E Van Der Pol
, L De Rond
, W H Roos
, R B M Schasfoort

Marca Wauben, H Zuilhof, Leon WMM Terstappen

Cell Biology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Extracellular Vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state-dependent and their cargo can contain disease related information. Large tumor-derived EVs (tdEVs, > 1 μm) in blood from cancer patients are associated with poor outcome and changes in their number can be used to monitor therapy effectiveness. Whereas small tumor-derived EVs (

Original language	English
Article number	608
Number of pages	19
Journal	Frontiers in Oncology
Volume	10
DOIs	https://doi.org/10.3389/FONC.2020.00608
Publication status	Published - Jun 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Atomic Force Microscopy
Cell-Derived Microparticles
Electrochemistry
Exosomes
Flow Cytometry
Raman spectrum analysis
Scanning electron microscopy
Surface Plasmon Resonance
extracellular vesicles
fluorescence microscopy
transmission electron microscopy 3

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Rikkert, L. G., Beekman, P., Caro, J., Coumans, F. A. W., Enciso Martinez, A., Jenster, G., Le Gac, S., Lee, W., Van Leeuwen, T. G., Loozen, G. B., Nanou, A., Nieuwland, R., Offerhaus, H. L., Otto, C., Pegtel, D. M., Piontek, M. C., Van Der Pol, E., De Rond, L., Roos, W. H., ... Terstappen, L. WMM. (2020). Cancer-ID: towards identification of cancer by tumor-derived extracellular vesicles in blood. Frontiers in Oncology, 10, Article 608. https://doi.org/10.3389/FONC.2020.00608

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abstract = "Extracellular Vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state-dependent and their cargo can contain disease related information. Large tumor-derived EVs (tdEVs, > 1 μm) in blood from cancer patients are associated with poor outcome and changes in their number can be used to monitor therapy effectiveness. Whereas small tumor-derived EVs (",

keywords = "Atomic Force Microscopy, Cell-Derived Microparticles, Electrochemistry, Exosomes, Flow Cytometry, Raman spectrum analysis, Scanning electron microscopy, Surface Plasmon Resonance, extracellular vesicles, fluorescence microscopy, transmission electron microscopy 3",

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year = "2020",

month = jun,

doi = "10.3389/FONC.2020.00608",

language = "English",

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journal = "Frontiers in Oncology",

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Rikkert, LG, Beekman, P, Caro, J, Coumans, FAW, Enciso Martinez, A, Jenster, G, Le Gac, S, Lee, W, Van Leeuwen, TG, Loozen, GB, Nanou, A, Nieuwland, R, Offerhaus, HL, Otto, C, Pegtel, DM, Piontek, MC, Van Der Pol, E, De Rond, L, Roos, WH, Schasfoort, RBM, Wauben, M, Zuilhof, H & Terstappen, LWMM 2020, 'Cancer-ID: towards identification of cancer by tumor-derived extracellular vesicles in blood', Frontiers in Oncology, vol. 10, 608. https://doi.org/10.3389/FONC.2020.00608

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AU - Rikkert, L G

AU - Beekman, P

AU - Caro, J

AU - Coumans, F A W

AU - Enciso Martinez, A

AU - Jenster, G

AU - Le Gac, S

AU - Lee, W

AU - Van Leeuwen, Ton G

AU - Loozen, G B

AU - Nanou, A

AU - Nieuwland, R

AU - Offerhaus, H L

AU - Otto, C

AU - Pegtel, D M

AU - Piontek, M C

AU - Van Der Pol, E

AU - De Rond, L

AU - Roos, W H

AU - Schasfoort, R B M

AU - Wauben, Marca

AU - Zuilhof, H

AU - Terstappen, Leon WMM

PY - 2020/6

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KW - Atomic Force Microscopy

KW - Cell-Derived Microparticles

KW - Electrochemistry

KW - Exosomes

KW - Flow Cytometry

KW - Raman spectrum analysis

KW - Scanning electron microscopy

KW - Surface Plasmon Resonance

KW - extracellular vesicles

KW - fluorescence microscopy

KW - transmission electron microscopy 3

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DO - 10.3389/FONC.2020.00608

M3 - Article

SN - 2234-943X

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JO - Frontiers in Oncology

JF - Frontiers in Oncology

M1 - 608

ER -

Cancer-ID: towards identification of cancer by tumor-derived extracellular vesicles in blood

Abstract

UN SDGs

Keywords

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