Body fluids after CO2 inhalation: Insight into panic mechanisms?

E. Griez; M. A. van den Hout; F. Verstappen

doi:10.1007/BF00377427

Body fluids after CO₂ inhalation: Insight into panic mechanisms?

E. Griez^*, M. A. van den Hout, F. Verstappen

^*Corresponding author for this work

Experimental psychopathology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Blood gases and electrolyte fluctuations were studied in arterial blood, after a single 35% CO₂-65% O₂ inhalation, which is known to trigger panic attacks in patients with panic disorder. The immediate effect of this maneuver was a brief hypercapnic acidosis followed by a slight alkalotic rebound, with shifts in Ca²⁺ and K⁺. The possible effect of these changes on neuronal membrane excitability is discussed, referring to recent experimental findings in panic provocation.

Original language	English
Pages (from-to)	369-371
Number of pages	3
Journal	European Archives of Psychiatry and Neurological Sciences
Volume	236
Issue number	6
DOIs	https://doi.org/10.1007/BF00377427
Publication status	Published - 1 Nov 1987

Keywords

CNS
CO2
Panic attacks
pH

Access to Document

10.1007/BF00377427

Cite this

@article{fb0257e34e82429d90213179409cae11,

title = "Body fluids after CO2 inhalation: Insight into panic mechanisms?",

abstract = "Blood gases and electrolyte fluctuations were studied in arterial blood, after a single 35% CO2-65% O2 inhalation, which is known to trigger panic attacks in patients with panic disorder. The immediate effect of this maneuver was a brief hypercapnic acidosis followed by a slight alkalotic rebound, with shifts in Ca2+ and K+. The possible effect of these changes on neuronal membrane excitability is discussed, referring to recent experimental findings in panic provocation.",

keywords = "CNS, CO2, Panic attacks, pH",

author = "E. Griez and {van den Hout}, {M. A.} and F. Verstappen",

year = "1987",

month = nov,

day = "1",

doi = "10.1007/BF00377427",

language = "English",

volume = "236",

pages = "369--371",

journal = "European Archives of Psychiatry and Neurological Sciences",

issn = "0175-758X",

publisher = "Springer",

number = "6",

}

TY - JOUR

T1 - Body fluids after CO2 inhalation

T2 - Insight into panic mechanisms?

AU - Griez, E.

AU - van den Hout, M. A.

AU - Verstappen, F.

PY - 1987/11/1

Y1 - 1987/11/1

N2 - Blood gases and electrolyte fluctuations were studied in arterial blood, after a single 35% CO2-65% O2 inhalation, which is known to trigger panic attacks in patients with panic disorder. The immediate effect of this maneuver was a brief hypercapnic acidosis followed by a slight alkalotic rebound, with shifts in Ca2+ and K+. The possible effect of these changes on neuronal membrane excitability is discussed, referring to recent experimental findings in panic provocation.

AB - Blood gases and electrolyte fluctuations were studied in arterial blood, after a single 35% CO2-65% O2 inhalation, which is known to trigger panic attacks in patients with panic disorder. The immediate effect of this maneuver was a brief hypercapnic acidosis followed by a slight alkalotic rebound, with shifts in Ca2+ and K+. The possible effect of these changes on neuronal membrane excitability is discussed, referring to recent experimental findings in panic provocation.

KW - CNS

KW - CO2

KW - Panic attacks

KW - pH

UR - http://www.scopus.com/inward/record.url?scp=0023517646&partnerID=8YFLogxK

U2 - 10.1007/BF00377427

DO - 10.1007/BF00377427

M3 - Article

C2 - 3119345

AN - SCOPUS:0023517646

SN - 0175-758X

VL - 236

SP - 369

EP - 371

JO - European Archives of Psychiatry and Neurological Sciences

JF - European Archives of Psychiatry and Neurological Sciences

IS - 6

ER -