Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry

Roe Vermeulen; Bo A. Jönsson; Christian H. Lindh; Hans Kromhout

doi:10.1007/s00420-005-0017-z

Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry

Roe Vermeulen
, Bo A. Jönsson
, Christian H. Lindh
, Hans Kromhout

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objectives: We studied the range in urinary levels of 2-thiothiazolidine-4-carboxyl acid (TTCA), a metabolite of CS2 and phthalic acid (PA), a common metabolite of phthalates, across factories and departments in the contemporary rubber manufacturing industry. Methods: Spot urine samples from 101 rubber workers employed in nine different factories were collected on Sunday and during the workweek on Tuesday, Wednesday and Thursday at ∼4 pm. In total, 386 urine samples were successfully analyzed. Results: Levels of both biomarkers increased significantly by a factor 2 (paired t-test P-value

Original language	English
Pages (from-to)	663-669
Number of pages	7
Journal	International Archives of Occupational and Environmental Health
Volume	78
Issue number	8
DOIs	https://doi.org/10.1007/s00420-005-0017-z
Publication status	Published - 1 Sept 2005

Keywords

Biomonitoring
Carbon disulphide
Phthalates
Rubber industry
biological marker
carbon disulfide
creatinine
disulfiram
dithiocarbamic acid derivative
ester
phthalic acid
plasticizer
article
biological monitoring
concentration (parameter)
controlled study
data analysis
human
human experiment
industrial worker
metabolite
occupational exposure
rubber industry
statistical analysis
urinalysis
working time

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10.1007/s00420-005-0017-z

Cite this

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title = "Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry",

abstract = "Objectives: We studied the range in urinary levels of 2-thiothiazolidine-4-carboxyl acid (TTCA), a metabolite of CS2 and phthalic acid (PA), a common metabolite of phthalates, across factories and departments in the contemporary rubber manufacturing industry. Methods: Spot urine samples from 101 rubber workers employed in nine different factories were collected on Sunday and during the workweek on Tuesday, Wednesday and Thursday at ∼4 pm. In total, 386 urine samples were successfully analyzed. Results: Levels of both biomarkers increased significantly by a factor 2 (paired t-test P-value",

keywords = "Biomonitoring, Carbon disulphide, Phthalates, Rubber industry, biological marker, carbon disulfide, creatinine, disulfiram, dithiocarbamic acid derivative, ester, phthalic acid, plasticizer, article, biological monitoring, concentration (parameter), controlled study, data analysis, human, human experiment, industrial worker, metabolite, occupational exposure, rubber industry, statistical analysis, urinalysis, working time",

author = "Roe Vermeulen and J{\"o}nsson, \{Bo A.\} and Lindh, \{Christian H.\} and Hans Kromhout",

year = "2005",

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TY - JOUR

T1 - Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry

AU - Vermeulen, Roe

AU - Jönsson, Bo A.

AU - Lindh, Christian H.

AU - Kromhout, Hans

PY - 2005/9/1

Y1 - 2005/9/1

N2 - Objectives: We studied the range in urinary levels of 2-thiothiazolidine-4-carboxyl acid (TTCA), a metabolite of CS2 and phthalic acid (PA), a common metabolite of phthalates, across factories and departments in the contemporary rubber manufacturing industry. Methods: Spot urine samples from 101 rubber workers employed in nine different factories were collected on Sunday and during the workweek on Tuesday, Wednesday and Thursday at ∼4 pm. In total, 386 urine samples were successfully analyzed. Results: Levels of both biomarkers increased significantly by a factor 2 (paired t-test P-value

AB - Objectives: We studied the range in urinary levels of 2-thiothiazolidine-4-carboxyl acid (TTCA), a metabolite of CS2 and phthalic acid (PA), a common metabolite of phthalates, across factories and departments in the contemporary rubber manufacturing industry. Methods: Spot urine samples from 101 rubber workers employed in nine different factories were collected on Sunday and during the workweek on Tuesday, Wednesday and Thursday at ∼4 pm. In total, 386 urine samples were successfully analyzed. Results: Levels of both biomarkers increased significantly by a factor 2 (paired t-test P-value

KW - Biomonitoring

KW - Carbon disulphide

KW - Phthalates

KW - Rubber industry

KW - biological marker

KW - carbon disulfide

KW - creatinine

KW - disulfiram

KW - dithiocarbamic acid derivative

KW - ester

KW - phthalic acid

KW - plasticizer

KW - article

KW - biological monitoring

KW - concentration (parameter)

KW - controlled study

KW - data analysis

KW - human

KW - human experiment

KW - industrial worker

KW - metabolite

KW - occupational exposure

KW - rubber industry

KW - statistical analysis

KW - urinalysis

KW - working time

U2 - 10.1007/s00420-005-0017-z

DO - 10.1007/s00420-005-0017-z

M3 - Article

SN - 0340-0131

VL - 78

SP - 663

EP - 669

JO - International Archives of Occupational and Environmental Health

JF - International Archives of Occupational and Environmental Health

IS - 8

ER -

Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry

Abstract

Keywords

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