Abstract
Riboflavin (RF) is an essential water-soluble vitamin with unique biological and physicochemical properties such as transporterspecific cell internalization, implication in redox reactions, fluorescence and photosensitizing. Due to these features RF attracted researchers in various fields from targeted drug delivery and tissue engineering to optoelectronics and biosensors. In this review we will give a brief reminder of RF chemistry, its optical, photosensitizing properties, RF transporter systems and its role in pathologies. We will point a special attention on the recent findings concerning RF applications in nanotechnologies such as RF functionalized nanoparticles, polymers, biomolecules, carbon nanotubes, hydrogels and implants for tissue engineering.
Original language | English |
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Pages (from-to) | 121-33 |
Number of pages | 13 |
Journal | Biomaterials |
Volume | 80 |
DOIs | |
Publication status | Published - Feb 2016 |
Keywords
- Animals
- Biomedical Engineering
- Biosensing Techniques
- Humans
- Models, Molecular
- Nanomedicine
- Nanoparticles
- Nanotechnology
- Photosensitizing Agents
- Riboflavin
- Tissue Engineering
- Vitamin B Complex
- Journal Article
- Research Support, Non-U.S. Gov't
- Review