Abstract
The ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice, ferrets, and hamsters were shown to resist MERS-CoV infection. We inoculated rabbits with MERS-CoV. Although virus was detected in the lungs, neither significant histopathological changes nor clinical symptoms were observed. Infectious virus, however, was excreted from the upper respiratory tract, indicating a potential route of MERS-CoV transmission in some animal species.
Original language | English |
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Pages (from-to) | 6131-5 |
Number of pages | 5 |
Journal | Journal of Virology |
Volume | 89 |
Issue number | 11 |
DOIs | |
Publication status | Published - Jun 2015 |
Externally published | Yes |
Keywords
- Animals
- Asymptomatic Diseases
- Coronavirus Infections
- Cricetinae
- Disease Models, Animal
- Female
- Lung
- Mice
- Middle East Respiratory Syndrome Coronavirus
- Rabbits
- Respiratory System
- Virus Shedding
- Journal Article
- Research Support, N.I.H., Extramural
- Research Support, Non-U.S. Gov't