Artificial scotoma estimation based on population receptive field mapping

A Hummer; M Ritter; M Woletz; A A Ledolter; M Tik; S O Dumoulin; G E Holder; U Schmidt-Erfurth; C Windischberger

doi:10.1016/j.neuroimage.2017.12.010

Artificial scotoma estimation based on population receptive field mapping

A Hummer, M Ritter, M Woletz, A A Ledolter, M Tik, S O Dumoulin, G E Holder, U Schmidt-Erfurth, C Windischberger

MR Centre of Excellence, Centre for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Department of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Department of Ophthalmology, National University of Singapore & National University Hospital, 1E Kent Ridge Road, Singapore 119228, Singapore; UCL Institute of Ophthalmology, University College London, 11-43 Bath Street, London EC1V 9EL, UK.
MR Centre of Excellence, Centre for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. Electronic address: [email protected].
extern

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Population receptive field (pRF) mapping based on functional magnetic resonance imaging (fMRI) is an ideal method for obtaining detailed retinotopic information. One particularly promising application of pRF mapping is the estimation and quantification of visual field effects, for example scotomata in patients suffering from macular dysfunction or degeneration (MD) or hemianopic defects in patients with intracranial dysfunction. However, pRF mapping performance is influenced by a number of factors including spatial and temporal resolution, distribution of dural venous sinuses and patient performance. This study addresses the ability of current pRF methodology to assess the size of simulated scotomata in healthy individuals. The data demonstrate that central scotomata down to a radius of 2.35° (4.7° diameter) visual angle can be reliably estimated in single subjects using high spatial resolution protocols and multi-channel receive array coils.

Original language	English
Pages (from-to)	342-351
Number of pages	10
Journal	NeuroImage
Volume	169
DOIs	https://doi.org/10.1016/j.neuroimage.2017.12.010
Publication status	Published - 1 Apr 2018
Externally published	Yes

Keywords

Adult
Brain Mapping/methods
Female
Healthy Volunteers
Humans
Magnetic Resonance Imaging
Male
Pattern Recognition, Visual/physiology
Perceptual Masking/physiology
Scotoma/diagnostic imaging
Visual Cortex/diagnostic imaging
Visual Fields/physiology
Young Adult

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10.1016/j.neuroimage.2017.12.010

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title = "Artificial scotoma estimation based on population receptive field mapping",

abstract = "Population receptive field (pRF) mapping based on functional magnetic resonance imaging (fMRI) is an ideal method for obtaining detailed retinotopic information. One particularly promising application of pRF mapping is the estimation and quantification of visual field effects, for example scotomata in patients suffering from macular dysfunction or degeneration (MD) or hemianopic defects in patients with intracranial dysfunction. However, pRF mapping performance is influenced by a number of factors including spatial and temporal resolution, distribution of dural venous sinuses and patient performance. This study addresses the ability of current pRF methodology to assess the size of simulated scotomata in healthy individuals. The data demonstrate that central scotomata down to a radius of 2.35° (4.7° diameter) visual angle can be reliably estimated in single subjects using high spatial resolution protocols and multi-channel receive array coils.",

keywords = "Adult, Brain Mapping/methods, Female, Healthy Volunteers, Humans, Magnetic Resonance Imaging, Male, Pattern Recognition, Visual/physiology, Perceptual Masking/physiology, Scotoma/diagnostic imaging, Visual Cortex/diagnostic imaging, Visual Fields/physiology, Young Adult",

author = "A Hummer and M Ritter and M Woletz and Ledolter, {A A} and M Tik and Dumoulin, {S O} and Holder, {G E} and U Schmidt-Erfurth and C Windischberger",

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doi = "10.1016/j.neuroimage.2017.12.010",

language = "English",

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T1 - Artificial scotoma estimation based on population receptive field mapping

AU - Hummer, A

AU - Ritter, M

AU - Woletz, M

AU - Ledolter, A A

AU - Tik, M

AU - Dumoulin, S O

AU - Holder, G E

AU - Schmidt-Erfurth, U

AU - Windischberger, C

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Population receptive field (pRF) mapping based on functional magnetic resonance imaging (fMRI) is an ideal method for obtaining detailed retinotopic information. One particularly promising application of pRF mapping is the estimation and quantification of visual field effects, for example scotomata in patients suffering from macular dysfunction or degeneration (MD) or hemianopic defects in patients with intracranial dysfunction. However, pRF mapping performance is influenced by a number of factors including spatial and temporal resolution, distribution of dural venous sinuses and patient performance. This study addresses the ability of current pRF methodology to assess the size of simulated scotomata in healthy individuals. The data demonstrate that central scotomata down to a radius of 2.35° (4.7° diameter) visual angle can be reliably estimated in single subjects using high spatial resolution protocols and multi-channel receive array coils.

AB - Population receptive field (pRF) mapping based on functional magnetic resonance imaging (fMRI) is an ideal method for obtaining detailed retinotopic information. One particularly promising application of pRF mapping is the estimation and quantification of visual field effects, for example scotomata in patients suffering from macular dysfunction or degeneration (MD) or hemianopic defects in patients with intracranial dysfunction. However, pRF mapping performance is influenced by a number of factors including spatial and temporal resolution, distribution of dural venous sinuses and patient performance. This study addresses the ability of current pRF methodology to assess the size of simulated scotomata in healthy individuals. The data demonstrate that central scotomata down to a radius of 2.35° (4.7° diameter) visual angle can be reliably estimated in single subjects using high spatial resolution protocols and multi-channel receive array coils.

KW - Adult

KW - Brain Mapping/methods

KW - Female

KW - Healthy Volunteers

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Pattern Recognition, Visual/physiology

KW - Perceptual Masking/physiology

KW - Scotoma/diagnostic imaging

KW - Visual Cortex/diagnostic imaging

KW - Visual Fields/physiology

KW - Young Adult

U2 - 10.1016/j.neuroimage.2017.12.010

DO - 10.1016/j.neuroimage.2017.12.010

M3 - Article

C2 - 29253656

SN - 1053-8119

VL - 169

SP - 342

EP - 351

JO - NeuroImage

JF - NeuroImage

ER -

Artificial scotoma estimation based on population receptive field mapping

Abstract

Keywords

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