Artificial Metalloenzymes for Hydrogenation and Transfer Hydrogenation Reactions

Manuel Basauri-molina; Robertus J. M. Klein Gebbink

doi:10.1002/9783527804085.ch6

Artificial Metalloenzymes for Hydrogenation and Transfer Hydrogenation Reactions

Manuel Basauri-molina, Robertus J. M. Klein Gebbink

Sub Organic Chemistry and Catalysis

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

The development of artificial hydrogenases (AHases) and transfer hydrogenases (ATHases) has played a leading and guiding role for the field of artificial metalloenzymes. Starting from the early studies by Whitesides and coworkers, this chapter showcases the conceptual development of AHases and ATHases, highlighting the different conjugation strategies used for their construction and exemplifying the stereoselective control in product formation that can be reached.

Original language	English
Title of host publication	Artificial Metalloenzymes and MetalloDNAzymes in Catalysis
Subtitle of host publication	From Design to Applications
Publisher	Wiley - VCH Verlag GmbH & CO. KGaA
Pages	171-197
ISBN (Electronic)	9783527804085
ISBN (Print)	9783527341788
DOIs	https://doi.org/10.1002/9783527804085.ch6
Publication status	Published - 25 Mar 2018

Keywords

artificial metalloenzymes
catalytic hydrogenation
transfer hydrogenation
directed evolution
enantioselectivity
rhodium
ruthenium
iridium

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10.1002/9783527804085.ch6

basauri-molinaFinal published version, 1.14 MBLicence: Taverne

Cite this

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abstract = "The development of artificial hydrogenases (AHases) and transfer hydrogenases (ATHases) has played a leading and guiding role for the field of artificial metalloenzymes. Starting from the early studies by Whitesides and coworkers, this chapter showcases the conceptual development of AHases and ATHases, highlighting the different conjugation strategies used for their construction and exemplifying the stereoselective control in product formation that can be reached.",

keywords = "artificial metalloenzymes, catalytic hydrogenation, transfer hydrogenation, directed evolution, enantioselectivity, rhodium, ruthenium, iridium",

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N2 - The development of artificial hydrogenases (AHases) and transfer hydrogenases (ATHases) has played a leading and guiding role for the field of artificial metalloenzymes. Starting from the early studies by Whitesides and coworkers, this chapter showcases the conceptual development of AHases and ATHases, highlighting the different conjugation strategies used for their construction and exemplifying the stereoselective control in product formation that can be reached.

AB - The development of artificial hydrogenases (AHases) and transfer hydrogenases (ATHases) has played a leading and guiding role for the field of artificial metalloenzymes. Starting from the early studies by Whitesides and coworkers, this chapter showcases the conceptual development of AHases and ATHases, highlighting the different conjugation strategies used for their construction and exemplifying the stereoselective control in product formation that can be reached.

KW - artificial metalloenzymes

KW - catalytic hydrogenation

KW - transfer hydrogenation

KW - directed evolution

KW - enantioselectivity

KW - rhodium

KW - ruthenium

KW - iridium

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DO - 10.1002/9783527804085.ch6

M3 - Chapter

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BT - Artificial Metalloenzymes and MetalloDNAzymes in Catalysis

PB - Wiley - VCH Verlag GmbH & CO. KGaA

ER -

Artificial Metalloenzymes for Hydrogenation and Transfer Hydrogenation Reactions

Abstract

Keywords

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