Anthracene functionalized thermosensitive and UV-crosslinkable polymeric micelles

Yang Shi; Renata M. Cardoso; Cornelus F. Van Nostrum; Wim E. Hennink

doi:10.1039/c4py01759e

Anthracene functionalized thermosensitive and UV-crosslinkable polymeric micelles

Yang Shi
, Renata M. Cardoso
, Cornelus F. Van Nostrum
, Wim E. Hennink^*

^*Corresponding author for this work

Utrecht University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

An anthracene-functionalized thermosensitive block copolymer was synthesized, which formed micelles by heating its aqueous solution above the lower critical solution temperature (LCST). The micelles were subsequently crosslinked by UV illumination at 365 nm with a normal handheld UV lamp. The micelles showed a small size (30 nm) and high loading capacity (16.0 ± 0.1%) for paclitaxel and released paclitaxel for more than ten days.

Original language	English
Pages (from-to)	2048-2053
Number of pages	6
Journal	Polymer Chemistry
Volume	6
Issue number	11
DOIs	https://doi.org/10.1039/c4py01759e
Publication status	Published - 1 Jan 2015

Access to Document

10.1039/c4py01759e

59eFinal published version, 1.1 MB

Cite this

@article{c00ce44265474f4a9fc4445250237ffe,

title = "Anthracene functionalized thermosensitive and UV-crosslinkable polymeric micelles",

abstract = "An anthracene-functionalized thermosensitive block copolymer was synthesized, which formed micelles by heating its aqueous solution above the lower critical solution temperature (LCST). The micelles were subsequently crosslinked by UV illumination at 365 nm with a normal handheld UV lamp. The micelles showed a small size (30 nm) and high loading capacity (16.0 ± 0.1\%) for paclitaxel and released paclitaxel for more than ten days.",

author = "Yang Shi and Cardoso, \{Renata M.\} and \{Van Nostrum\}, \{Cornelus F.\} and Hennink, \{Wim E.\}",

year = "2015",

month = jan,

day = "1",

doi = "10.1039/c4py01759e",

language = "English",

volume = "6",

pages = "2048--2053",

journal = "Polymer Chemistry",

issn = "1759-9954",

publisher = "Royal Society of Chemistry",

number = "11",

}

TY - JOUR

T1 - Anthracene functionalized thermosensitive and UV-crosslinkable polymeric micelles

AU - Shi, Yang

AU - Cardoso, Renata M.

AU - Van Nostrum, Cornelus F.

AU - Hennink, Wim E.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - An anthracene-functionalized thermosensitive block copolymer was synthesized, which formed micelles by heating its aqueous solution above the lower critical solution temperature (LCST). The micelles were subsequently crosslinked by UV illumination at 365 nm with a normal handheld UV lamp. The micelles showed a small size (30 nm) and high loading capacity (16.0 ± 0.1%) for paclitaxel and released paclitaxel for more than ten days.

AB - An anthracene-functionalized thermosensitive block copolymer was synthesized, which formed micelles by heating its aqueous solution above the lower critical solution temperature (LCST). The micelles were subsequently crosslinked by UV illumination at 365 nm with a normal handheld UV lamp. The micelles showed a small size (30 nm) and high loading capacity (16.0 ± 0.1%) for paclitaxel and released paclitaxel for more than ten days.

UR - https://www.scopus.com/pages/publications/84924034467

U2 - 10.1039/c4py01759e

DO - 10.1039/c4py01759e

M3 - Article

AN - SCOPUS:84924034467

SN - 1759-9954

VL - 6

SP - 2048

EP - 2053

JO - Polymer Chemistry

JF - Polymer Chemistry

IS - 11

ER -

Anthracene functionalized thermosensitive and UV-crosslinkable polymeric micelles

Abstract

Access to Document

Other files and links

Fingerprint

Cite this