Anomalous dynamics of unbiased polymer translocation through a narrow pore

Debabrata Panja*, Gerard T. Barkema, Robin C. Ball

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We consider a polymer of length N translocating through a narrow pore in the absence of external fields. The characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics is anomalous up to the Rouse time tau(R) similar to N(1+2 nu) ., with a mean square displacement through the pore consistent with t((1+nu)/( 1+ 2 nu)), with nu approximate to 0.588 the Flory exponent. This is shown to be directly related to a decay over time of the excess monomer density near the pore as t(-(1+nu)/(1+2 nu)) exp(-t/tau(R)). Beyond the Rouse time, translocation becomes diffusive. In consequence of this, the dwell time tau(d), the time a translocating polymer typically spends within the pore, scales as N(2+nu), in contrast to previous claims.

Original languageEnglish
Article number432202
Number of pages8
JournalJournal of physics. Condensed matter
Volume19
Issue number43
DOIs
Publication statusPublished - 31 Oct 2007

Keywords

  • PROTEIN TRANSLOCATION
  • POLYNUCLEOTIDE MOLECULES
  • DNA TRANSLOCATION
  • NANOPORE
  • MEMBRANES
  • CHANNEL
  • MODEL
  • ACID
  • DISCRIMINATION
  • SIMULATIONS

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