An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)

Stanley E Althof; Chris G McMahon; Marcel D Waldinger; Ege Can Serefoglu; Alan W Shindel; P Ganesan Adaikan; Edgardo Becher; John Dean; Francois Giuliano; Wayne J G Hellstrom; Annamaria Giraldi; Sidney Glina; Luca Incrocci; Emmanuele Jannini; Marita McCabe; Sharon Parish; David Rowland; R Taylor Segraves; Ira Sharlip; Luiz Otavio Torres

doi:10.1111/jsm.12504

An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)

Stanley E Althof, Chris G McMahon, Marcel D Waldinger, Ege Can Serefoglu, Alan W Shindel, P Ganesan Adaikan, Edgardo Becher, John Dean, Francois Giuliano, Wayne J G Hellstrom, Annamaria Giraldi, Sidney Glina, Luca Incrocci, Emmanuele Jannini, Marita McCabe, Sharon Parish, David Rowland, R Taylor Segraves, Ira Sharlip, Luiz Otavio Torres

Pharmacology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

INTRODUCTION: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts.

AIM: The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts.

METHOD: A comprehensive literature review was performed.

RESULTS: This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients.

CONCLUSION: Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.

Original language	English
Pages (from-to)	1392-1422
Number of pages	31
Journal	Journal of Sexual Medicine
Volume	11
Issue number	6
DOIs	https://doi.org/10.1111/jsm.12504
Publication status	Published - Jun 2014

Bibliographical note

Keywords

Ablation Techniques
Acupuncture Therapy
Combined Modality Therapy
Drug Evaluation
Ejaculation
Humans
Male
Medical History Taking
Off-Label Use
Patient Education as Topic
Physical Examination
Physician's Role
Premature Ejaculation
Primary Health Care
Psychotherapy
Sexual Partners

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10.1111/jsm.12504

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Althof_et_al-2014-The_Journal_of_Sexual_Medicine
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Althof, S. E., McMahon, C. G., Waldinger, M. D., Serefoglu, E. C., Shindel, A. W., Adaikan, P. G., Becher, E., Dean, J., Giuliano, F., Hellstrom, W. J. G., Giraldi, A., Glina, S., Incrocci, L., Jannini, E., McCabe, M., Parish, S., Rowland, D., Segraves, R. T., Sharlip, I., & Torres, L. O. (2014). An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE). Journal of Sexual Medicine, 11(6), 1392-1422. https://doi.org/10.1111/jsm.12504

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abstract = "INTRODUCTION: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts.AIM: The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts.METHOD: A comprehensive literature review was performed.RESULTS: This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients.CONCLUSION: Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.",

keywords = "Ablation Techniques, Acupuncture Therapy, Combined Modality Therapy, Drug Evaluation, Ejaculation, Humans, Male, Medical History Taking, Off-Label Use, Patient Education as Topic, Physical Examination, Physician's Role, Premature Ejaculation, Primary Health Care, Psychotherapy, Sexual Partners",

author = "Althof, {Stanley E} and McMahon, {Chris G} and Waldinger, {Marcel D} and Serefoglu, {Ege Can} and Shindel, {Alan W} and Adaikan, {P Ganesan} and Edgardo Becher and John Dean and Francois Giuliano and Hellstrom, {Wayne J G} and Annamaria Giraldi and Sidney Glina and Luca Incrocci and Emmanuele Jannini and Marita McCabe and Sharon Parish and David Rowland and Segraves, {R Taylor} and Ira Sharlip and Torres, {Luiz Otavio}",

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year = "2014",

month = jun,

doi = "10.1111/jsm.12504",

language = "English",

volume = "11",

pages = "1392--1422",

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Althof, SE, McMahon, CG, Waldinger, MD, Serefoglu, EC, Shindel, AW, Adaikan, PG, Becher, E, Dean, J, Giuliano, F, Hellstrom, WJG, Giraldi, A, Glina, S, Incrocci, L, Jannini, E, McCabe, M, Parish, S, Rowland, D, Segraves, RT, Sharlip, I & Torres, LO 2014, 'An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)', Journal of Sexual Medicine, vol. 11, no. 6, pp. 1392-1422. https://doi.org/10.1111/jsm.12504

TY - JOUR

T1 - An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)

AU - Althof, Stanley E

AU - McMahon, Chris G

AU - Waldinger, Marcel D

AU - Serefoglu, Ege Can

AU - Shindel, Alan W

AU - Adaikan, P Ganesan

AU - Becher, Edgardo

AU - Dean, John

AU - Giuliano, Francois

AU - Hellstrom, Wayne J G

AU - Giraldi, Annamaria

AU - Glina, Sidney

AU - Incrocci, Luca

AU - Jannini, Emmanuele

AU - McCabe, Marita

AU - Parish, Sharon

AU - Rowland, David

AU - Segraves, R Taylor

AU - Sharlip, Ira

AU - Torres, Luiz Otavio

PY - 2014/6

Y1 - 2014/6

N2 - INTRODUCTION: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts.AIM: The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts.METHOD: A comprehensive literature review was performed.RESULTS: This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients.CONCLUSION: Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.

AB - INTRODUCTION: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts.AIM: The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts.METHOD: A comprehensive literature review was performed.RESULTS: This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients.CONCLUSION: Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years.

KW - Ablation Techniques

KW - Acupuncture Therapy

KW - Combined Modality Therapy

KW - Drug Evaluation

KW - Ejaculation

KW - Humans

KW - Male

KW - Medical History Taking

KW - Off-Label Use

KW - Patient Education as Topic

KW - Physical Examination

KW - Physician's Role

KW - Premature Ejaculation

KW - Primary Health Care

KW - Psychotherapy

KW - Sexual Partners

U2 - 10.1111/jsm.12504

DO - 10.1111/jsm.12504

M3 - Article

C2 - 24848686

SN - 1743-6095

VL - 11

SP - 1392

EP - 1422

JO - Journal of Sexual Medicine

JF - Journal of Sexual Medicine

IS - 6

ER -

An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE)

Abstract

Bibliographical note

Keywords

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