TY - JOUR
T1 - Agricoh, a newly formed consortium of agricultural cohorts
AU - Leon, M.E.
AU - Freeman, Laura Beane
AU - Douwes, Jeroen
AU - Hoppin, Jane
AU - Kromhout, Hans
AU - Lebailly, Pierre
AU - Nordby, K.C.
AU - Schenker, Marc
AU - Schüz, Joachim
AU - Waring, S.C.
AU - Alavanja, Michael
AU - Annesi-Maesano, Isabelle
AU - Baldi, I.
AU - Dalvie, Mohamed Aqiel
AU - Ferro, G.
AU - Fervers, B.
AU - Langseth, H.
AU - London, Leslie
AU - Straif, Kurt
AU - Blair, Aaron
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Objectives We recently formed AGRICOH, a consortium of agricultural cohort studies, offering the opportunity to investigate potential health effects of a wide range of occupational and environmental exposures coexisting in agriculture. Methods and results AGRICOH is a consortium of 22 agricultural cohort studies initiated by US National Cancer Institute (NCI) and coordinated by International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries in 5 continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate associations between a wide range of agricultural exposures (eg, pesticides, diesel exhausts, organic dust, inorganic dust, mycotoxins, endotoxins, viruses) and a wide range of health outcomes (eg, cancer, respiratory, neurologic, auto-immune diseases, as well as reproductive and allergic disorders and injuries), with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (eg, use of infrequently applied pesticides) or relatively rare outcomes (eg, certain types of cancer, neurologic and autoimmune diseases). To facilitate future projects need for data harmonisation is required and underway. Characteristics of cohorts integrating AGRICOH, the wide range of exposures data available, data harmonisation challenges and research concepts will be illustrated. Conclusions AGRICOH represents a great resource for conducting validation of exposure assessment and etiologic studies in association with a wide array of exposures unique to, or showing the highest likelihood of exposure, in the agricultural setting.
AB - Objectives We recently formed AGRICOH, a consortium of agricultural cohort studies, offering the opportunity to investigate potential health effects of a wide range of occupational and environmental exposures coexisting in agriculture. Methods and results AGRICOH is a consortium of 22 agricultural cohort studies initiated by US National Cancer Institute (NCI) and coordinated by International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries in 5 continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate associations between a wide range of agricultural exposures (eg, pesticides, diesel exhausts, organic dust, inorganic dust, mycotoxins, endotoxins, viruses) and a wide range of health outcomes (eg, cancer, respiratory, neurologic, auto-immune diseases, as well as reproductive and allergic disorders and injuries), with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (eg, use of infrequently applied pesticides) or relatively rare outcomes (eg, certain types of cancer, neurologic and autoimmune diseases). To facilitate future projects need for data harmonisation is required and underway. Characteristics of cohorts integrating AGRICOH, the wide range of exposures data available, data harmonisation challenges and research concepts will be illustrated. Conclusions AGRICOH represents a great resource for conducting validation of exposure assessment and etiologic studies in association with a wide array of exposures unique to, or showing the highest likelihood of exposure, in the agricultural setting.
KW - pesticide
KW - mycotoxin
KW - endotoxin
KW - epidemiology
KW - occupational health
KW - exposure
KW - neoplasm
KW - cohort analysis
KW - autoimmune disease
KW - health
KW - virus
KW - diseases
KW - injury
KW - environmental exposure
KW - agriculture
KW - national health organization
KW - international cooperation
KW - South Africa
KW - Canada
KW - Costa Rica
KW - New Zealand
KW - Denmark
KW - France
KW - Norway
KW - exhaust gas
KW - organic dust
KW - dust
KW - Korea
U2 - 10.1136/oemed-2011-100382.353
DO - 10.1136/oemed-2011-100382.353
M3 - Article
SN - 1351-0711
VL - 68
SP - 106
JO - Occupational and Environmental Medicine
JF - Occupational and Environmental Medicine
ER -