Agricoh, a newly formed consortium of agricultural cohorts

M.E. Leon, Laura Beane Freeman, Jeroen Douwes, Jane Hoppin, Hans Kromhout, Pierre Lebailly, K.C. Nordby, Marc Schenker, Joachim Schüz, S.C. Waring, Michael Alavanja, Isabelle Annesi-Maesano, I. Baldi, Mohamed Aqiel Dalvie, G. Ferro, B. Fervers, H. Langseth, Leslie London, Kurt Straif, Aaron Blair

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    Objectives We recently formed AGRICOH, a consortium of agricultural cohort studies, offering the opportunity to investigate potential health effects of a wide range of occupational and environmental exposures coexisting in agriculture. Methods and results AGRICOH is a consortium of 22 agricultural cohort studies initiated by US National Cancer Institute (NCI) and coordinated by International Agency for Research on Cancer (IARC) since October 2010. The consortium includes cohorts from 9 countries in 5 continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). AGRICOH aspires to promote and sustain collaboration and pooling of data to investigate associations between a wide range of agricultural exposures (eg, pesticides, diesel exhausts, organic dust, inorganic dust, mycotoxins, endotoxins, viruses) and a wide range of health outcomes (eg, cancer, respiratory, neurologic, auto-immune diseases, as well as reproductive and allergic disorders and injuries), with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (eg, use of infrequently applied pesticides) or relatively rare outcomes (eg, certain types of cancer, neurologic and autoimmune diseases). To facilitate future projects need for data harmonisation is required and underway. Characteristics of cohorts integrating AGRICOH, the wide range of exposures data available, data harmonisation challenges and research concepts will be illustrated. Conclusions AGRICOH represents a great resource for conducting validation of exposure assessment and etiologic studies in association with a wide array of exposures unique to, or showing the highest likelihood of exposure, in the agricultural setting.
    Original languageEnglish
    Pages (from-to)106
    Number of pages1
    JournalOccupational and Environmental Medicine
    Volume68
    DOIs
    Publication statusPublished - 1 Sept 2011

    Keywords

    • pesticide
    • mycotoxin
    • endotoxin
    • epidemiology
    • occupational health
    • exposure
    • neoplasm
    • cohort analysis
    • autoimmune disease
    • health
    • virus
    • diseases
    • injury
    • environmental exposure
    • agriculture
    • national health organization
    • international cooperation
    • South Africa
    • Canada
    • Costa Rica
    • New Zealand
    • Denmark
    • France
    • Norway
    • exhaust gas
    • organic dust
    • dust
    • Korea

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