Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics

Igor A. Kaltashov; Cedric E. Bobst; Rinat R. Abzalimov; Guanbo Wang; Burcu Baykal; Shunhai Wang

doi:10.1016/j.biotechadv.2011.05.006

Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics

Igor A. Kaltashov, Cedric E. Bobst, Rinat R. Abzalimov, Guanbo Wang, Burcu Baykal, Shunhai Wang

extern

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	210-222
Journal	Biotechnology Advances
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/j.biotechadv.2011.05.006
Publication status	Published - 2012
Externally published	Yes

Keywords

Biopharmaceuticals
Protein drugs
Biologics
Protein structure
Post-translational modification
Protein conformation
Aggregation
Therapeutic target
Analytical characterization
Pharmacokinetics

Access to Document

10.1016/j.biotechadv.2011.05.006

Cite this

@article{e94052702b854159b40dc49741ee7a5b,

title = "Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics",

keywords = "Biopharmaceuticals, Protein drugs, Biologics, Protein structure, Post-translational modification, Protein conformation, Aggregation, Therapeutic target, Analytical characterization, Pharmacokinetics",

author = "Kaltashov, {Igor A.} and Bobst, {Cedric E.} and Abzalimov, {Rinat R.} and Guanbo Wang and Burcu Baykal and Shunhai Wang",

year = "2012",

doi = "10.1016/j.biotechadv.2011.05.006",

language = "English",

volume = "30",

pages = "210--222",

journal = "Biotechnology Advances",

issn = "0734-9750",

publisher = "Elsevier Inc.",

number = "1",

}

Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics. / Kaltashov, Igor A.; Bobst, Cedric E.; Abzalimov, Rinat R. et al.
In: Biotechnology Advances, Vol. 30, No. 1, 2012, p. 210-222.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics

AU - Kaltashov, Igor A.

AU - Bobst, Cedric E.

AU - Abzalimov, Rinat R.

AU - Wang, Guanbo

AU - Baykal, Burcu

AU - Wang, Shunhai

PY - 2012

Y1 - 2012

KW - Biopharmaceuticals

KW - Protein drugs

KW - Biologics

KW - Protein structure

KW - Post-translational modification

KW - Protein conformation

KW - Aggregation

KW - Therapeutic target

KW - Analytical characterization

KW - Pharmacokinetics

U2 - 10.1016/j.biotechadv.2011.05.006

DO - 10.1016/j.biotechadv.2011.05.006

M3 - Article

SN - 0734-9750

VL - 30

SP - 210

EP - 222

JO - Biotechnology Advances

JF - Biotechnology Advances

IS - 1

ER -