TY - JOUR
T1 - Acute effects of ambient ozone on pulmonary function of children in the Netherlands
AU - Hoek, G.
AU - Fischer, P.
AU - Brunekreef, B.
AU - Lebret, E.
AU - Hofschreuder, P.
AU - Mennen, M. G.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1993
Y1 - 1993
N2 - In the spring and summer of 1989 an epidemiologic study was conducted to evaluate the acute effects of photochemical air pollution episodes on pulmonary function of children living in three nonindustrial towns in the Netherlands. Spirometry was performed repeatedly in the schools of the children, mostly during the morning hours. Data from 533 children having more than four valid pulmonary function tests were included in the analyses. The association between previous-day ambient ozone concentration and pulmonary function was evaluated, using individual linear regression analysis and subsequent evaluation of the distribution of individual regression coefficients. One hour maximum ambient ozone concentrations frequently exceeded 160 μg/m3 but were all lower than the Dutch Air Quality Guideline of 240 μg/m3 for all three populations. Significant negative associations of previous-day ambient ozone with FVC, FEV1, peak expiratory flow (PEF), and maximal midexpiratory flow (MMEF) were observed. There were indications of systematic differences in responses among the children. Children with chronic respiratory symptoms did not have a stronger response than children without these symptoms.
AB - In the spring and summer of 1989 an epidemiologic study was conducted to evaluate the acute effects of photochemical air pollution episodes on pulmonary function of children living in three nonindustrial towns in the Netherlands. Spirometry was performed repeatedly in the schools of the children, mostly during the morning hours. Data from 533 children having more than four valid pulmonary function tests were included in the analyses. The association between previous-day ambient ozone concentration and pulmonary function was evaluated, using individual linear regression analysis and subsequent evaluation of the distribution of individual regression coefficients. One hour maximum ambient ozone concentrations frequently exceeded 160 μg/m3 but were all lower than the Dutch Air Quality Guideline of 240 μg/m3 for all three populations. Significant negative associations of previous-day ambient ozone with FVC, FEV1, peak expiratory flow (PEF), and maximal midexpiratory flow (MMEF) were observed. There were indications of systematic differences in responses among the children. Children with chronic respiratory symptoms did not have a stronger response than children without these symptoms.
UR - http://www.scopus.com/inward/record.url?scp=0027392348&partnerID=8YFLogxK
U2 - 10.1164/ajrccm/147.1.111
DO - 10.1164/ajrccm/147.1.111
M3 - Article
C2 - 8420403
AN - SCOPUS:0027392348
SN - 0003-0805
VL - 147
SP - 111
EP - 117
JO - American Review of Respiratory Disease
JF - American Review of Respiratory Disease
IS - 1
ER -
