Acromegaly in a non-diabetic cat

Federico Fracassi, Margherita Salsi, Federica Sammartano, Stefano Bo, Hans S Kooistra

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    CASE SUMMARY: A 14-year-old, neutered male European shorthair cat was evaluated for a routine health check. The owner did not report any clinical signs except for respiratory stridor. On physical examination the main findings were broad facial features and increased interdental spaces. On haematology, a mild, non-regenerative anaemia was detected, whereas the serum biochemistry profile and urinalysis were unremarkable. The serum glucose concentration was within the reference interval. Serum insulin-like growth factor-1 concentration was markedly elevated (>1600 ng/ml). The basal serum growth hormone concentration was elevated and decreased only mildly after somatostatin administration. Basal serum insulin concentration was high, and the insulin concentration increased considerably after glucose loading, consistent with insulin resistance. CT scanning of the skull showed an enlarged pituitary gland and increased skull bone thickness. The final diagnosis was acromegaly.

    RELEVANCE AND NOVEL INFORMATION: These findings demonstrate that acromegaly should be pursued and suspected in cats other than those with diabetes mellitus.

    Original languageEnglish
    Pages (from-to)1-4
    JournalJFMS open reports
    Volume2
    Issue number1
    DOIs
    Publication statusPublished - 2016

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