A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features

J. Schüz; S.J. Schonfeld; H. Kromhout; K. Straif; S.V. Kashanskiy; E.V. Kovalevskiy; I.V. Bukhtiyarov; V. McCormack

doi:10.1016/j.canep.2013.03.001

A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features

J. Schüz, S.J. Schonfeld, H. Kromhout, K. Straif, S.V. Kashanskiy, E.V. Kovalevskiy, I.V. Bukhtiyarov, V. McCormack

extern

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Chrysotile, a serpentine asbestos fibre, is the only type of asbestos produced and consumed in the world today. It is an established human carcinogen. We have begun fieldwork on a retrospective cohort study of employees of one of the world's largest chrysotile mine and mills, situated in Asbest, Russia. The primary aim of the study is to better characterize and quantify the risk of cancer mortality in terms of (i) the dose-response relationship of exposure with risk; (ii) the range of cancer sites affected, including female-specific cancers; and (iii) effects of duration of exposure and latency periods. This information will expand our understanding of the scale of the impending cancer burden due to chrysotile, including if chrysotile use ceased worldwide forthwith. Herein we describe the scientific rationale for conducting this study and the main features of its study design.

Original language	English
Pages (from-to)	440-445
Number of pages	6
Journal	Cancer Epidemiology
Volume	37
Issue number	4
DOIs	https://doi.org/10.1016/j.canep.2013.03.001
Publication status	Published - 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.canep.2013.03.001

Cite this

@article{c5bfa3d6325640059a336d7bd60d20e2,

title = "A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features",

abstract = "Chrysotile, a serpentine asbestos fibre, is the only type of asbestos produced and consumed in the world today. It is an established human carcinogen. We have begun fieldwork on a retrospective cohort study of employees of one of the world's largest chrysotile mine and mills, situated in Asbest, Russia. The primary aim of the study is to better characterize and quantify the risk of cancer mortality in terms of (i) the dose-response relationship of exposure with risk; (ii) the range of cancer sites affected, including female-specific cancers; and (iii) effects of duration of exposure and latency periods. This information will expand our understanding of the scale of the impending cancer burden due to chrysotile, including if chrysotile use ceased worldwide forthwith. Herein we describe the scientific rationale for conducting this study and the main features of its study design.",

author = "J. Sch{\"u}z and S.J. Schonfeld and H. Kromhout and K. Straif and S.V. Kashanskiy and E.V. Kovalevskiy and I.V. Bukhtiyarov and V. McCormack",

year = "2013",

doi = "10.1016/j.canep.2013.03.001",

language = "English",

volume = "37",

pages = "440--445",

journal = "Cancer Epidemiology",

issn = "1877-7821",

publisher = "Elsevier Ltd",

number = "4",

}

TY - JOUR

T1 - A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features

AU - Schüz, J.

AU - Schonfeld, S.J.

AU - Kromhout, H.

AU - Straif, K.

AU - Kashanskiy, S.V.

AU - Kovalevskiy, E.V.

AU - Bukhtiyarov, I.V.

AU - McCormack, V.

PY - 2013

Y1 - 2013

N2 - Chrysotile, a serpentine asbestos fibre, is the only type of asbestos produced and consumed in the world today. It is an established human carcinogen. We have begun fieldwork on a retrospective cohort study of employees of one of the world's largest chrysotile mine and mills, situated in Asbest, Russia. The primary aim of the study is to better characterize and quantify the risk of cancer mortality in terms of (i) the dose-response relationship of exposure with risk; (ii) the range of cancer sites affected, including female-specific cancers; and (iii) effects of duration of exposure and latency periods. This information will expand our understanding of the scale of the impending cancer burden due to chrysotile, including if chrysotile use ceased worldwide forthwith. Herein we describe the scientific rationale for conducting this study and the main features of its study design.

AB - Chrysotile, a serpentine asbestos fibre, is the only type of asbestos produced and consumed in the world today. It is an established human carcinogen. We have begun fieldwork on a retrospective cohort study of employees of one of the world's largest chrysotile mine and mills, situated in Asbest, Russia. The primary aim of the study is to better characterize and quantify the risk of cancer mortality in terms of (i) the dose-response relationship of exposure with risk; (ii) the range of cancer sites affected, including female-specific cancers; and (iii) effects of duration of exposure and latency periods. This information will expand our understanding of the scale of the impending cancer burden due to chrysotile, including if chrysotile use ceased worldwide forthwith. Herein we describe the scientific rationale for conducting this study and the main features of its study design.

U2 - 10.1016/j.canep.2013.03.001

DO - 10.1016/j.canep.2013.03.001

M3 - Article

SN - 1877-7821

VL - 37

SP - 440

EP - 445

JO - Cancer Epidemiology

JF - Cancer Epidemiology

IS - 4

ER -

A retrospective cohort study of cancer mortality in employees of a Russian chrysotile asbestos mine and mills: study rationale and key features

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this