TY - JOUR
T1 - A practical route toward the preparation of 4,5:7,8‐di‐O‐isopropylidene KDO ethyl ester
AU - Boons, G. J.P.H.
AU - van der Klein, P. A.M.
AU - van der Marel, G. A.
AU - van Boom, J. H.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - Condensation of 2,3: 5,6‐di‐O‐isopropylidene‐D‐mannopyranose with (ethoxycarbonylmethylene)triphenylphosphorane afforded the expected Wittig product. Reaction of the latter with chlorotrimethylsilane followed by methyl methanethiosulfate, in the presence of I. DA and after removal of the trimethylsilyl and unmasking of the dimethyl thioketal function, gave the title compound in a good overall yield.
AB - Condensation of 2,3: 5,6‐di‐O‐isopropylidene‐D‐mannopyranose with (ethoxycarbonylmethylene)triphenylphosphorane afforded the expected Wittig product. Reaction of the latter with chlorotrimethylsilane followed by methyl methanethiosulfate, in the presence of I. DA and after removal of the trimethylsilyl and unmasking of the dimethyl thioketal function, gave the title compound in a good overall yield.
UR - http://www.scopus.com/inward/record.url?scp=84987100707&partnerID=8YFLogxK
U2 - 10.1002/recl.19901090403
DO - 10.1002/recl.19901090403
M3 - Article
AN - SCOPUS:84987100707
SN - 0165-0513
VL - 109
SP - 273
EP - 276
JO - Recueil des Travaux Chimiques des Pays‐Bas
JF - Recueil des Travaux Chimiques des Pays‐Bas
IS - 4
ER -