A Dopaminergic Basis for Fear Extinction

Raffael Kalisch; Anna M V Gerlicher; Sevil Duvarci

doi:10.1016/j.tics.2019.01.013

A Dopaminergic Basis for Fear Extinction

Raffael Kalisch, Anna M V Gerlicher, Sevil Duvarci

Research output: Contribution to journal › Review article › peer-review

Abstract

It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.

Original language	English
Pages (from-to)	274-277
Number of pages	4
Journal	Trends in Cognitive Sciences
Volume	23
Issue number	4
DOIs	https://doi.org/10.1016/j.tics.2019.01.013
Publication status	Published - Apr 2019
Externally published	Yes

Bibliographical note

Keywords

Animals
Dopamine/physiology
Extinction, Psychological/physiology
Fear/physiology
Humans
Memory, Long-Term/physiology

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10.1016/j.tics.2019.01.013

Cite this

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title = "A Dopaminergic Basis for Fear Extinction",

abstract = "It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.",

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author = "Raffael Kalisch and Gerlicher, {Anna M V} and Sevil Duvarci",

year = "2019",

month = apr,

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journal = "Trends in Cognitive Sciences",

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AU - Kalisch, Raffael

AU - Gerlicher, Anna M V

AU - Duvarci, Sevil

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N2 - It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.

AB - It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.

KW - Animals

KW - Dopamine/physiology

KW - Extinction, Psychological/physiology

KW - Fear/physiology

KW - Humans

KW - Memory, Long-Term/physiology

U2 - 10.1016/j.tics.2019.01.013

DO - 10.1016/j.tics.2019.01.013

M3 - Review article

C2 - 30803871

SN - 1364-6613

VL - 23

SP - 274

EP - 277

JO - Trends in Cognitive Sciences

JF - Trends in Cognitive Sciences

IS - 4

ER -

A Dopaminergic Basis for Fear Extinction

Abstract

Bibliographical note

Keywords

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Cite this