3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.

I. Antolino-Lobo, J. Meulenbelt, S.M. Nijmeijer, R.F.M. Maas-Bakker, I. Meijerman, M. van den Berg, M.B.M. van Duursen

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Pharmacology, Toxicology and Pharmaceutical Science