Research output per year
Research output per year
- 1 - 50 out of 174 results
Search results
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2020
Bio-ink development for three-dimensional bioprinting of hetero-cellular cartilage constructs
Mouser, V. H. M., Levato, R., Mensinga, A., Dhert, W. J. A., Gawlitta, D. & Malda, J., 2020, In: Connective Tissue Research. 61, 2, p. 137-151 15 p.Research output: Contribution to journal › Article › Academic › peer-review
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Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration
Krouwels, A., Iljas, J. D., Kragten, A. H. M., Dhert, W. J. A., Öner, F. C., Tryfonidou, M. A. & Creemers, L. B., 14 Apr 2020, In: International Journal of Molecular Sciences. 21, 8, 18 p.Research output: Contribution to journal › Article › Academic › peer-review
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2019
Effect of biomaterial electrical charge on in vivo bone formation
Olthof, M. G. L., Kempen, D. H. R., Liu, X., Dadsetan, M., Tryfonidou, M. A., Yaszemski, M. J., Dhert, W. & Lu, L., Jul 2019, In: Tissue Engineering. Part A. 25, 13/14, p. 1037-1052Research output: Contribution to journal › Article › Academic › peer-review
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PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation
Rutgers, M., Bach, F., Vonk, L., van Rijen, M., Akrum, V., van Boxtel, A., Dhert, W. & Creemers, L., 1 Apr 2019, In: PLoS One. 14, 4, e0213483.Research output: Contribution to journal › Article › Academic › peer-review
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The osteoinductive effect of controlled BMP-2 release is location-dependent
Olthof, M. G. L., Lu, L., Tryfonidou, M. A., Loozen, L., Pouran, B., Yaszemski, M. J., Meij, B., Dhert, W., Alblas, J. & Kempen, D. H. R., Feb 2019, In: Tissue Engineering. Part A. 25, 3-4, p. 193-202Research output: Contribution to journal › Article › Academic › peer-review
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2018
Bone morphogenetic protein-2 release profile modulates bone formation in phosphorylated hydrogel
Olthof, M. G. L., Kempen, D. H. R., Liu, X., Dadsetan, M., Tryfonidou, M. A., Yaszemski, M. J., Dhert, W. J. A. & Lu, L., 31 Mar 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 6, p. 1339-1351Research output: Contribution to journal › Article › Academic › peer-review
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Comparing Hydrogels for Human Nucleus Pulposus Regeneration: Role of Osmolarity during Expansion
Krouwels, A., Melchels, F. P. W., van Rijen, M. H. P., Öner, F. C., Dhert, W. J. A., Tryfonidou, M. A. & Creemers, L. B., Apr 2018, In: Tissue Engineering - Part C: Methods. 24, 4Research output: Contribution to journal › Article › Academic › peer-review
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Ex vivo model unravelling cell distribution effect in hydrogels for cartilage repair
Mouser, V. H. M., Dautzenberg, N. M. M., Levato, R., van Rijen, M. H. P., Dhert, W. J. A., Malda, J. & Gawlitta, D., 2018, In: Altex. 35, 1, p. 65-76Research output: Contribution to journal › Article › Academic › peer-review
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Focal adhesion signaling affects regeneration by human nucleus pulposus cells in collagen- but not carbohydrate-based hydrogels
Krouwels, A., Melchels, F. P. W., van Rijen, M. H. P., Ten Brink, C. B. M., Dhert, W. J. A., Cumhur Öner, F., Tryfonidou, M. A. & Creemers, L. B., 15 Jan 2018, In: Acta Biomaterialia. 66, p. 238-247 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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In Vitro and In Vivo Correlation of BMP-2 Release Profiles from Complex Delivery Vehicles
Olthof, M. G. L., Tryfonidou, M. A., Dadsetan, M., Dhert, W., Yaszemski, M. J., Kempen, D. H. R. & Lu, L., 1 Jul 2018, In: Tissue engineering. Part C, Methods. 24, 7, p. 379-390Research output: Contribution to journal › Article › Academic › peer-review
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No effects of Hyperosmolar Culture medium on Tissue Regeneration by Human Degenerated Nucleus Pulposus Cells despite Upregulation Extracellular Matrix Genes
Krouwels, A., Popov-Celeketic, J., Plomp, S. G. M., Dhert, W. J. A., Öner, F. C., Bank, R. A. & Creemers, L. B., 1 Mar 2018, In: Spine. 43, 5, p. 307-315Research output: Contribution to journal › Article › Academic › peer-review
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Phosphate functional groups improve OPF osteoconduction and BMP-2 osteoinductive efficacy
Olthof, M. G. L., Tryfonidou, M., Liu, X., Pouran, B., Meij, B., Dhert, W., Yaszemski, M. J., Lu, L., Alblas, J. & Kempen, D. H. R., May 2018, In: Tissue Engineering - Part A.. 24, 9-10, p. 819-829Research output: Contribution to journal › Article › Academic › peer-review
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2017
3D bioprinting of methacrylated hyaluronic acid (MeHA) hydrogel with intrinsic osteogenicity
Poldervaart, M. T., Goversen, B., De Ruijter, M., Abbadessa, A., Melchels, F. P. W., Öner, F. C., Dhert, W. J. A., Vermonden, T. & Alblas, J., 1 Jun 2017, In: PLoS One. 12, 6, p. 1-15 15 p., e0177628.Research output: Contribution to journal › Article › Academic › peer-review
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Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons
de Windt, T. S., Vonk, L. A., Slaper-Cortenbach, I. C. M., van den Broek, M. P. H., Nizak, R., van Rijen, M. H. P., de Weger, R. A., Dhert, W. J. A. & Saris, D. B. F., Jan 2017, In: Stem Cells. 35, 1, p. 256-264Research output: Contribution to journal › Article › Academic › peer-review
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Effect of different sustained bone morphogenetic protein-2 release kinetics on bone formation in poly(propylene fumarate) scaffolds
Olthof, M. G. L., Kempen, D. H. R., Herrick, J. L., Yaszemski, M. J., Dhert, W. J. A. & Lu, L., 10 Feb 2017, In: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 106, 2, p. 477-487Research output: Contribution to journal › Article › Academic › peer-review
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Hyaluronic Acid-Based Hydrogel Coating Does Not Affect Bone Apposition at the Implant Surface in a Rabbit Model
Boot, W., Gawlitta, D., Nikkels, P. G. J., Pouran, B., van Rijen, M. H. P., Dhert, W. J. A. & Vogely, H. C., Jul 2017, In: Clinical Orthopaedics and Related Research. 245, 7, p. 1911-1919 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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Local induction of inflammation affects bone formation
Croes, M., Kruyt, M. C., Loozen, L., Kragten, A. H., Yuan, H., Dhert, W. J., Öner, F. C. & Alblas, J., 27 Feb 2017, In: European Cells and Materials. 33, p. 211-226 16 p.Research output: Contribution to journal › Article › Academic › peer-review
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Safety of intradiscal injection and biocompatibility of polyester amide microspheres in a canine model predisposed to intervertebral disc degeneration
Willems, N., Mihov, G., Grinwis, G. C. M., van Dijk, M., Schumann, D., Bos, C., Strijkers, G. J., Dhert, W. J. A., Meij, B. P., Creemers, L. B. & Tryfonidou, M. A., May 2017, In: Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 105, 4, p. 707-714Research output: Contribution to journal › Article › Academic › peer-review
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Triblock copolymers based on ε-caprolactone and trimethylene carbonate for the 3D printing of tissue engineering scaffolds
Güney, A., Malda, J., Dhert, W. J. A. & Grijpma, D. W., Apr 2017, In: International Journal of Artificial Organs. 40, 4, p. 133-204Research output: Contribution to journal › Article › Academic › peer-review
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2016
A Synthetic Thermosensitive Hydrogel for Cartilage Bioprinting and Its Biofunctionalization with Polysaccharides
Abbadessa, A., Mouser, V. H. M., Blokzijl, M. M., Gawlitta, D., Dhert, W. J. A., Hennink, W. E., Malda, J. & Vermonden, T., 13 Jun 2016, In: Biomacromolecules. 17, 6, p. 2137-2147Research output: Contribution to journal › Article › Academic › peer-review
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Establishment of an Early Vascular Network Promotes the Formation of Ectopic Bone
Eman, R. M., Meijer, H. A. W., Öner, F. C., Dhert, W. J. A. & Alblas, J., 12 Feb 2016, In: Tissue Engineering. Part A. 22, 3-4, p. 253-62 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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OP-1 Compared with Iliac Crest Autograft in Instrumented Posterolateral Fusion: A Randomized, Multicenter Non-Inferiority Trial
Delawi, D., Jacobs, W., van Susante, J. L. C., Rillardon, L., Prestamburgo, D., Specchia, N., Gay, E., Verschoor, N., Garcia-Fernandez, C., Guerado, E., Quarles van Ufford, H., Kruyt, M. C., Dhert, W. J. A. & Oner, F. C., 16 Mar 2016, In: Journal of Bone and Joint Surgery - Series A. 98, 6, p. 441-8 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Proinflammatory T cells and IL-17 stimulate osteoblast differentiation
Croes, M., Öner, F. C., van Neerven, D., Sabir, E., Kruyt, M. C., Blokhuis, T. J., Dhert, W. J. A. & Alblas, J., 2016, In: Bone. 84, p. 262-270 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting
Mouser, V. H. M., Melchels, F. P. W., Visser, J., Dhert, W. J. A., Gawlitta, D. & Malda, J., 2016, In: Biofabrication. 8, 3, 035003.Research output: Contribution to journal › Article › Academic › peer-review
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2015
A novel injectable thermoresponsive and cytocompatible gel of poly(N-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3D culture
Yang, H.-Y., van Ee, R. J., Timmer, K., Craenmehr, E. G. M., Huang, J. H., Öner, F. C., Dhert, W. J. A., Kragten, A. H. M., Willems, N., Grinwis, G. C. M., Tryfonidou, M. A., Papen-Botterhuis, N. E. & Creemers, L. B., 2015, In: Acta Biomaterialia.Research output: Contribution to journal › Article › Academic › peer-review
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Arthroscopic airbrush assisted cell implantation for cartilage repair in the knee: a controlled laboratory and human cadaveric study
de Windt, T. S., Vonk, L. A., Buskermolen, J. K., Visser, J., Karperien, M., Bleys, R. L. A. W., Dhert, W. J. A. & Saris, D. B. F., Jan 2015, In: Osteoarthritis and Cartilage. 23, 1, p. 143-150 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Biocompatibility and intradiscal application of a thermoreversible celecoxib-loaded poly-N-isopropylacrylamide MgFe-layered double hydroxide hydrogel in a canine model
Willems, N., Yang, H.-Y., Langelaan, M. L. P., Tellegen, A. R., Grinwis, G. C. M., Kranenburg, H.-J. C., Riemers, F. M., Plomp, S. G. M., Craenmehr, E. G. M., Dhert, W. J. A., Papen-Botterhuis, N. E., Meij, B. P., Creemers, L. B. & Tryfonidou, M., Aug 2015, In: Arthritis Research & Therapy. 17, 1, 214.Research output: Contribution to journal › Article › Academic › peer-review
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Bone morphogenetic protein-2 nonviral gene therapy in a goat iliac crest model for bone formation
Loozen, L. D., van der Helm, Y. J. M., Öner, F. C., Dhert, W. J. A., Kruyt, M. C. & Alblas, J., 2015, In: Tissue Engineering. Part A. 21, 9-10, p. 1672-1679 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Cartilage regeneration using zonal chondrocyte subpopulations: a promising approach or an overcomplicated strategy?
Schuurman, W., Klein, T. J., Dhert, W. J. A., van Weeren, P. R., Hutmacher, D. W. & Malda, J., Jun 2015, In: Journal of Tissue Engineering and Regenerative Medicine. 9, 6, p. 669-678 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Combination of bone morphogenetic protein-2 plasmid DNA with chemokine CXCL12 creates an additive effect on bone formation onset and volume
Wegman, F., Poldervaart, M. T., van der Helm, Y. J., Oner, F. C., Dhert, W. J. & Alblas, J., 27 Jul 2015, In: European Cells and Materials. 30, p. 1-10; discussion 10-1Research output: Contribution to journal › Article › Academic › peer-review
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Crosslinkable Hydrogels Derived from Cartilage, Meniscus, and Tendon Tissue
Visser, J., Levett, P. A., te Moller, N. C. R., Besems, J., Boere, K. W. M., van Rijen, M. H. P., de Grauw, J. C., Dhert, W. J. A., van Weeren, P. R. & Malda, J., 1 Apr 2015, In: Tissue Engineering. Part A. 21, 7-8, p. 1195-1206 12 p.Research output: Contribution to journal › Article › Academic › peer-review
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Decellularized Cartilage-Derived Matrix as Substrate for Endochondral Bone Regeneration
Gawlitta, D., Benders, K. E. M., Visser, J., van der Sar, A. S., Kempen, D. H. R., Theyse, L. F. H., Malda, J. & Dhert, W. J. A., 19 Feb 2015, In: Tissue Engineering. Part A. 21, 3-4, p. 694-703Research output: Contribution to journal › Article › Academic › peer-review
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Direct Cell-Cell Contact with Chondrocytes Is a Key Mechanism in Multipotent Mesenchymal Stromal Cell-Mediated Chondrogenesis
de Windt, T. S., Saris, D. B. F., Slaper-Cortenbach, I. C. M., van Rijen, M. H. P., Gawlitta, D., Creemers, L. B., de Weger, R. A., Dhert, W. J. A. & Vonk, L. A., 12 Aug 2015, In: Tissue Engineering. Part A. 21, 19-20, p. 2536-2547 12 p.Research output: Contribution to journal › Article › Academic › peer-review
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Endochondral bone formation in gelatin methacrylamide hydrogel with embedded cartilage-derived matrix particles
Visser, J., Gawlitta, D., Benders, K. E. M., Toma, S. M. H., Pouran, B., van Weeren, P. R., Dhert, W. J. A. & Malda, J., Jan 2015, In: Biomaterials. 37, p. 174-182 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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Growth factor-induced osteogenesis in a novel radiolucent bone chamber
Poldervaart, M. T., van der Stok, J., de Haas, M., ‘T Hart, M. C., Öner, F. C., Dhert, W. J. A., Weinans, H. & Alblas, J., 2015, In: European Cells & Materials [E]. 29, p. 35-41 7 p.Research output: Contribution to journal › Article › Academic › peer-review
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Intradiscal application of rhBMP-7 does not induce regeneration in a canine model of spontaneous intervertebral disc degeneration
Willems, N., Bach, F. C., Plomp, S. G. M., van Rijen, M. H., Wolfswinkel, J., Grinwis, G. C., Bos, C., Strijkers, G. J., Dhert, W. J., Meij, B. P., Creemers, L. B. & Tryfonidou, M. A., 2015, In: Arthritis Research & Therapy. 17, p. 1-14 14 p., 137.Research output: Contribution to journal › Article › Academic › peer-review
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Missed low-grade infection in suspected aseptic loosening has no consequences for the survival of total hip arthroplasty
Boot, W., Moojen, D. J. F., Visser, E., Lehr, A. M., De Windt, T. S., Van Hellemondt, G., Geurts, J., Tulp, N. J. A., Schreurs, B. W., Burger, B. J., Dhert, W. J. A., Gawlitta, D. & Vogely, H. C., 2015, In: Acta Orthopaedica. 86, 6, p. 678-83 6 p.Research output: Contribution to journal › Article › Academic › peer-review
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Osteoarthritis treatment using autologous conditioned serum after placebo
Rutgers, M., Creemers, L. B., Yang, K. G. A., Raijmakers, N. J. H., Dhert, W. J. A. & Saris, D. B. F., 2015, In: Acta Orthopaedica. 86, 1, p. 114–118 5 p.Research output: Contribution to journal › Article › Academic › peer-review
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Participant selection for preventive Regenerative Medicine trials: ethical challenges of selecting individuals at risk
Niemansburg, S. L., Habets, M. G. J. L., Dhert, W. J. A., van Delden, J. J. M. & Bredenoord, A. L., Nov 2015, In: Journal of Medical Ethics. 41, 11, p. 914-916 3 p.Research output: Contribution to journal › Article › Academic › peer-review
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Potential Conflicts of Interest of Editorial Board Members from Five Leading Spine Journals
Janssen, S. J., Bredenoord, A. L., Dhert, W., de Kleuver, M., Oner, F. C. & Verlaan, J.-J., 5 Jun 2015, In: PLoS One. 10, 6, 11 p., e0127362.Research output: Contribution to journal › Article › Academic › peer-review
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Proinflammatory Mediators Enhance the Osteogenesis of Human Mesenchymal Stem Cells after Lineage Commitment
Croes, M., Oner, F. C., Kruyt, M. C., Blokhuis, T. J., Bastian, O., Dhert, W. J. A. & Alblas, J., 2015, In: PLoS One. 10, 7, 14 p., e0132781.Research output: Contribution to journal › Article › Academic › peer-review
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Reconsidering the ethics of sham interventions in an era of emerging technologies
Niemansburg, S. L., van Delden, J. J. M., Dhert, W. J. A. & Bredenoord, A. L., Apr 2015, In: Surgery. 157, 4, p. 801-10 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Reinforcement of hydrogels using three-dimensionally printed microfibres
Visser, J., Melchels, F. P. W., Jeon, J. E., van Bussel, E. M., Kimpton, L. S., Byrne, H. M., Dhert, W. J. A., Dalton, P. D., Hutmacher, D. W. & Malda, J., 2015, In: Nature Communications [E]. 6, 10 p., 6933.Research output: Contribution to journal › Article › Academic › peer-review
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Societal impacts of regenerative medicine: reflections on the views of orthopedic professionals
Niemansburg, S. L., Tempels, T. H., Dhert, W. J. A., van Delden, J. J. M. & Bredenoord, A. L., 2015, In: Regenerative Medicine. 10, 1, p. 17-24 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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2014
Applicability of a Newly Developed Bioassay for Determining Bioactivity of Anti-Inflammatory Compounds in Release Studies - Celecoxib and Triamcinolone Acetonide Released from Novel PLGA-Based Microspheres
Yang, H.-Y., van Dijk, M., Licht, R., Beekhuizen, M., van Rijen, M., Janstål, M. K., Oner, F. C., Dhert, W. J. A., Schumann, D. & Creemers, L. B., 28 Aug 2014, In: Pharmaceutical Research. 2015, 32, p. 680-690Research output: Contribution to journal › Article › Academic › peer-review
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BMPs Enhance in Vitro Tissue Regeneration by Human Degenerated Nucleus Pulposus Cells
Krouwels, A., Iljas, L., Plomp, S., Dhert, W., Oner, C. & Creemers, L. B., May 2014, In: Global Spine Journal. 4, 1_suppl, p. s-0034-1376562-s-0034-1376562Research output: Contribution to journal › Article › Academic › peer-review
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Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells
Yang, H.-Y., Vonk, L. A., Licht, R., van Boxtel, A. M. G., Bekkers, J. E. J., Kragten, A. H. M., Hein, S., Varghese, O. P., Howard, K. A., Öner, F. C., Dhert, W. J. A. & Creemers, L. B., 2014, In: European Journal of Pharmaceutical Sciences. 53, p. 35-44 10 p.Research output: Contribution to journal › Article › Academic › peer-review
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Chondrogenic potential of articular chondrocytes depends on their original location
Bekkers, J. E. J., Saris, D. B. F., Tsuchida, A. I., van Rijen, M. H. P., Dhert, W. J. A. & Creemers, L. B., Feb 2014, In: Tissue Engineering. Part A. 20, 3-4, p. 663-71 9 p.Research output: Contribution to journal › Article › Academic › peer-review
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Clinical outcome after traumatic spinal fractures in patients with ankylosing spinal disorders compared with control patients.
Westerveld, L. A., van Bemmel, J. C., Dhert, W. J. A., Öner, F. C. & Verlaan, J. J., 2014, In: The Spine Journal. 14, 5, p. 729-740 12 p.Research output: Contribution to journal › Article › Academic › peer-review
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Concise review: unraveling stem cell cocultures in regenerative medicine: which cell interactions steer cartilage regeneration and how?
de Windt, T. S., Hendriks, J. A., Zhao, X., Vonk, L. A., Creemers, L. B., Dhert, W. J. A., Randolph, M. A. & Saris, D. B. F., 2014, In: Stem cells translational medicine. 3, 6, p. 723-733 11 p.Research output: Contribution to journal › Article › Academic › peer-review