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Protein damage control: new molecular strategies for protein aggregation diseases such as Alzheimer or Huntington, exploiting the cellular chaperone machinery
Link to Utrecht University staff page
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Publication network from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FibrilPaint to determine the length of Tau amyloids in fluids
Aragonès Pedrola, J., Dekker, F. A., Garfagnini, T., Mayer, G., Koopman, M. B., Bergmeijer, M., Heesink, G., Rots, I., Claessens, M. M. A. E., Förster, F., Hoozemans, J. J. M., Jensen, H., Friedler, A. & Rüdiger, S. G. D., 27 Oct 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 44, e2502847122.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Specific phosphorylation patterns control the interplay between aggregation and condensation of Tau-R4 peptides
Bressler, S. G., Grunhaus, D., Aviram, A., Rüdiger, S. G. D., Hurevich, M. & Friedler, A., 7 Aug 2025, In: Organic & Biomolecular Chemistry. 23, 29, p. 6912-6923 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
A Peptide Strategy for Inhibiting Different Protein Aggregation Pathways
Garfagnini, T., Ferrari, L., Koopman, M. B., Dekker, F. A., Halters, S., Van Kappel, E., Mayer, G., Bressler, S., Maurice, M. M., Rüdiger, S. G. D. & Friedler, A., 16 Sept 2024, In: Chemistry - A European Journal. 30, 52, e202400080.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Peptides for the detection of amyloid fibril aggregates
Rüdiger, S. (Inventor), Dekker, F. (Inventor), Aragonès Pedrola, J. (Inventor), Friedler, A. (Inventor), Mayer, G. (Inventor) & Garfagnini, T. (Inventor), 31 Aug 2023, 31 Aug 2023, Priority No. EP23194706Research output: Patent › Academic
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How do protein aggregates escape quality control in neurodegeneration?
Koopman, M. B., Ferrari, L. & Rüdiger, S. G. D., Apr 2022, In: Trends in Neurosciences. 45, 4, p. 257-271 15 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile
In the media
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Utrechtse scheikundigen kunnen met nieuwe 'verfmethode' vroegtijdig dementie vaststellen: 'Een echte mijlpaal'
5/11/25
1 Media contribution
Press/Media: Research
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Dementia Proteins: New Diagnosis & Treatment Breakthroughs
29/10/25
1 Media contribution
Press/Media: Research