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The use of chemical proteomics strategies to study protein lipidation and small molecule - drug interactions

Link to Utrecht University staff page

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Publication network from the last five years

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  • Site-Specific Competitive Kinase Inhibitor Target Profiling Using Phosphonate Affinity Tags

    van Bergen, W., Nederstigt, A. E., Heck, A. J. R. & Baggelaar, M. P., Feb 2025, In: Molecular and Cellular Proteomics. 24, 2, 12 p., 100906.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation

    Ocasio, C. A., Baggelaar, M. P., Sipthorp, J., Losada de la Lastra, A., Tavares, M., Volarić, J., Soudy, C., Storck, E. M., Houghton, J. W., Palma-Duran, S. A., MacRae, J. I., Tomić, G., Carr, L., Downward, J., Eggert, U. S. & Tate, E. W., Oct 2024, In: Nature Biotechnology. 42, 10, p. 1548-1558 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders

    Kaiyrzhanov, R., Rad, A., Lin, S.-J., Bertoli-Avella, A., Kallemeijn, W. W., Godwin, A., Zaki, M. S., Huang, K., Lau, T., Petree, C., Efthymiou, S., Ghayoor Karimiani, E., Hempel, M., Normand, E. A., Rudnik-Schöneborn, S., Schatz, U. A., Baggelaar, M. P., Ilyas, M., Sultan, T. & Alvi, J. R. & 69 others, Ganieva, M., Fowler, B., Aanicai, R., Akay Tayfun, G., Al Saman, A., Alswaid, A., Amiri, N., Asilova, N., Shotelersuk, V., Yeetong, P., Azam, M., Babaei, M., Bahrami Monajemi, G., Mohammadi, P., Samie, S., Banu, S. H., Basto, J. P., Kortüm, F., Bauer, M., Bauer, P., Beetz, C., Garshasbi, M., Hameed Issa, A., Eyaid, W., Ahmed, H., Hashemi, N., Hassanpour, K., Herman, I., Ibrohimov, S., Abdul-Majeed, B. A., Imdad, M., Isrofilov, M., Kaiyal, Q., Khan, S., Kirmse, B., Koster, J., Lourenço, C. M., Mitani, T., Moldovan, O., Murphy, D., Najafi, M., Pehlivan, D., Rocha, M. E., Salpietro, V., Schmidts, M., Shalata, A., Mahroum, M., Talbeya, J. K., Taylor, R. W., Vazquez, D., Vetro, A., Waterham, H. R., Zaman, M., Schrader, T. A., Chung, W. K., Guerrini, R., Lupski, J. R., Gleeson, J., Suri, M., Jamshidi, Y., Bhatia, K. P., Vona, B., Schrader, M., Severino, M., Guille, M., Tate, E. W., Varshney, G. K., Houlden, H. & Maroofian, R., Apr 2024, In: Brain. 147, 4, p. 1436-1456 21 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • Dual-Probe Activity-Based Protein Profiling Reveals Site-Specific Differences in Protein Binding of EGFR-Directed Drugs

    van Bergen, W., Zuna, K., Fiala, J., Pohl, E. E., Heck, A. J. R. & Baggelaar, M. P., 16 Aug 2024, In: ACS Chemical Biology. 19, 8, p. 1705-1718 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
  • Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis

    Tomić, G., Sheridan, C., Refermat, A. Y., Baggelaar, M. P., Sipthorp, J., Sudarshan, B., Ocasio, C. A., Suárez-Bonnet, A., Priestnall, S. L., Herbert, E., Tate, E. W. & Downward, J., 28 May 2024, In: Cell Reports. 43, 5, 114224.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access