Research output per year
Research output per year
Personal profile
About
Researcher, interested in bacterial-host interactions
Link to Utrecht University staff page
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Publication network from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Salmonella persisters undermine host immune defenses during antibiotic treatment.
Stapels, D. A. C., Hill, P., Westermann, A., Fisher, R., Thurston, T., Saliba, A.-E., Blommestein, I., Vogel, J. & Helaine, S., 7 Dec 2018, In: Science (New York, N.Y.). 362, 6419, p. 1156-1160Research output: Contribution to journal › Article › Academic › peer-review
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Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella.
Saliba, A.-E., Li, L., Westermann, A., Appenzeller, S., Stapels, D. A. C., Schulte, L., Helaine, S. & Vogel, J., 14 Nov 2016, In: Nature Microbiology.Research output: Contribution to journal › Article › Academic › peer-review
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Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors.
Stapels, D. A. C., Ramyar, K., Bischoff, M., von Köckritz-Blickwede, M., Milder, F., Ruyken, M., Eisenbeis, J., McWhorter, W., Herrmann, M., van Kessel, K., Geisbrecht, B. & Rooijakkers, S. H. M., 26 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. p. 13187-13192Research output: Contribution to journal › Article › Academic › peer-review
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Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria-mucus interactions
Floor, E., Su, J., Chatterjee, M., Kuipers, E. S., IJssennagger, N., Heidari, F., Giordano, L., Wubbolts, R. W., Mihăilă, S. M., Stapels, D. A. C., Vercoulen, Y. & Strijbis, K., 2025, In: Gut Microbes. 17, 1, p. 1-26 26 p., 2434685.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via Protein Kinase C
Segui-Perez, C., Stapels, D. A. C., Ma, Z., Su, J., Passchier, E., Westendorp, B., Wubbolts, R. W., Wu, W., van Putten, J. P. M. & Strijbis, K., Mar 2024, In: Journal of Cell Science. 137, 5Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile
In the media
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JAK-ing into M1/M2 Polarization SteErs Salmonella-Containing Macrophages Away from Immune Attack to Promote Bacterial Persistence
8/01/20
1 item of Media coverage
Press/Media: Expert Comment
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Sleeping bacteria survive antibiotic treatment and hijack the host immune system
Stapels, D. & Hill, P.
6/05/19
1 Media contribution
Press/Media: Research
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Bacterial ‘sleeper cells’ evade antibiotics and weaken defence against infection
7/12/18
1 item of Media coverage
Press/Media: Research
Prizes & Grants
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EMBO long-term fellowship: "Intracellular survival and persistence mechanism of Salmonella in immune cells"
Stapels, D. (Recipient), 2015
Prize: Fellowship awarded competitively
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FEMS short-term fellowship: "Modulation of neutrophil extracellular traps by three Staphylococcus aureus elastase inhibitors"
Stapels, D. (Recipient), 2012
Prize: Fellowship awarded competitively
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