Personal profile
About
Link to Utrecht University staff page
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 12 Responsible Consumption and Production -
SDG 13 Climate Action
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Publication network from the last five years
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Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
HPB Organoid Consortium, 6 May 2021, In: Cell Stem Cell. 28, 5, p. 816-832 17 p.Research output: Contribution to journal › Article › Academic
Open AccessFile -
Macrophage-derived Wnt opposes notch signaling to specify hepatic progenitor cell fate in chronic liver disease
Boulter, L., Govaere, O., Bird, T. G., Radulescu, S., Ramachandran, P., Pellicoro, A., Ridgway, R., Seo, S. S., Spee, B., van Rooijen, N., Sansom, O. J., Iredale, J. P., Lowell, S., Roskams, T. A. & Forbes, S. J., 2012, In: Nature Medicine. 18, 4, p. 572-579 8 p.Research output: Contribution to journal › Article › Academic › peer-review
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Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling
Spee, B., Carpino, G., Schotanus, B. A., Katoonizadeh, A., Vander Borght, S., Gaudio, E. & Roskams, T., 2010, In: Gut. 59, 2, p. 247-257 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Accelerated production of human epithelial organoids in a miniaturized spinning bioreactor
Ye, S., Marsee, A., van Tienderen, G. S., Rezaeimoghaddam, M., Sheikh, H., Samsom, R.-A., de Koning, E. J. P., Fuchs, S., Verstegen, M. M. A., van der Laan, L. J. W., van de Vosse, F., Malda, J., Ito, K., Spee, B. & Schneeberger, K., 18 Nov 2024, In: Cell Reports Methods. 4, 11, 100903.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile -
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
Nantasanti, S., Spee, B., Kruitwagen, H. S., Chen, C., Geijsen, N., Oosterhoff, L. A., van Wolferen, M. E., Pelaez, N., Fieten, H., Wubbolts, R. W., Grinwis, G. C., Chan, J., Huch, M., Vries, R. R. G., Clevers, H., de Bruin, A., Rothuizen, J., Penning, L. C. & Schotanus, B. A., 2015, In: Stem Cell Reports [E]. 5, 5, p. 895-907 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile
Activities
- 2 Invited talk
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Keratin 19 positive hepatocellular carcinomas express various hepatic progenitor cell markers
Spee, B. (Invited speaker)
6 Oct 2007Activity: Talk or presentation › Invited talk › Academic
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Human progenitor cells are surrounded by different subtypes of hepatic stellate cells/myofibroblasts in human liver diseases in relation to differentiation and fibrosis patterns
Spee, B. (Invited speaker)
14 Apr 2007Activity: Talk or presentation › Invited talk › Academic
In the media
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Interview Prof. dr. Roos Masereeuw over het Drug disposition On-a-Chip
7/10/25
1 Media contribution
Press/Media: Research
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Hoe Nederlandse onderzoekers pionieren met het printen van kunstlevers
16/05/25
1 Media contribution
Press/Media: Expert Comment
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Utrecht bewijst zich als spil in de regeneratieve geneeskunde
18/02/25
1 Media contribution
Press/Media: Expert Comment
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Utrecht University leads NEOLIVER project to revolutionise liver transplantation
4/02/25
1 Media contribution
Press/Media: Expert Comment
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Demcon neemt ontwikkelaar van bioreactor voor organoïden Orgonex over
4/02/25
1 Media contribution
Press/Media: Expert Comment
Prizes & Grants
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Visiting Postdoctoral Fellowship
Spee, B. (Recipient), 2007
Prize: Prize (including medals and awards)