Novel approaches for the evaluation of tumours and lymph nodes in dogs with near-infrared fluorescence, contrast-enhanced ultrasound and elastography

Activity: Examination › Member of an PhD examination committee › Academic

Description

Sentinel lymph node (SLN) mapping and subsequent evaluation of the SLN is a crucial step for staging of cancers that spread through the lymphatic system. The presence of metastases in the SLN is a negative prognostic indicator, since they disclose the metastatic potential of the primary tumour and distant metastases are an important cause of ultimate death in cancer patients. Besides metastatic disease, recurrence after incomplete surgical resection of the primary tumour will also shorten the patient’s survival time. The overall objective of this doctoral thesis was to investigate innovative imaging technologies in dogs that already demonstrated their potential in human diagnostic and surgical oncology, for the identification and evaluation of the SLN, and for the identification of cancerous tissue during surgical resection. Three evolving imaging techniques including near-infrared fluorescence (NIRF) imaging, contrast-enhanced ultrasound (CEUS), and shear wave elastography (SWE) were investigated.
Period10 Dec 2021
ExamineeSophie Favril
Examination held at
  • Ghent University
Degree of RecognitionInternational